@article{JGO1067,
author = {Cedrek McFadden and Brian McKinley and Brian Greenwell and Kaylee Knuckolls and Patrick Culumovic and David Schammel and Christine Schammel and Steven D Trocha},
title = {Differential lymph node retrieval in rectal cancer: associated factors and effect on survival},
journal = {Journal of Gastrointestinal Oncology},
volume = {4},
number = {2},
year = {2013},
keywords = {},
abstract = {Background: Recent publications have identified positive associations between numbers of lymph nodes pathologically examined and five-year overall survival (5-yr OS) in colon cancer. However, focused examinations of relationships between survival of rectal cancer and lymph node counts are less common. We conducted a single institution, retrospective review of rectal cancer resections to determine whether lymph node counts correlated with 5-yr OS and to explore the relationship between lymph node counts and various clinical and pathologic factors.
Methods: A retrospective review of our institutional tumor registry identified 159 patients with AJCC Stage 1, 2, or 3 rectal cancers that underwent surgical resection at our institution over eleven years. Univariate analysis was used to explore the relationship between lymph node counts and age, AJCC Stage, time period of diagnosis, preoperative radiotherapy, and performance of TME. Survival analysis was performed by the Kaplan-Meier method and the Cox proportional hazards model.
Results: In univariate analysis, there was an association between increased lymph node counts and age },
issn = {2219-679X}, url = {https://jgo.amegroups.org/article/view/1067}
}