How to cite item

Intratumoral PKM2 expression predicts benefit from adjuvant FOLFOX in stage II–III colorectal cancer

   
@article{JGO116886,
	author = {Eonwoo Shin and Hyo Sang Lee and Dae-Woon Eom and Jae Young Kwak and Kwan Mo Yang and Ho-Suk Oh and Sehee Kim and Chang Sik Yu},
	title = {Intratumoral PKM2 expression predicts benefit from adjuvant FOLFOX in stage II–III colorectal cancer},
	journal = {Journal of Gastrointestinal Oncology},
	volume = {17},
	number = {2},
	year = {2026},
	keywords = {},
	abstract = {Clinicopathological risk factors in non-metastatic colorectal cancer provide prognostic information but have limited ability to identify patients who benefit from specific adjuvant chemotherapy regimens. Pyruvate kinase M2 (PKM2), a key regulator of aerobic glycolysis and tumor proliferation, has been linked to chemotherapy sensitivity in a regimen-dependent manner. This study evaluated intratumoral PKM2 expression as a predictive biomarker for the effectiveness of oxaliplatin-based adjuvant chemotherapy in stage II/III colorectal cancer.},
	issn = {2219-679X},	url = {https://jgo.amegroups.org/article/view/116886}
}