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Splenectomy is an independent risk factor for poorer perioperative outcomes after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: an analysis of 936 procedures

   
@article{JGO14675,
	author = {Akshat Saxena and Winston Liauw and David L. Morris},
	title = {Splenectomy is an independent risk factor for poorer perioperative outcomes after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: an analysis of 936 procedures},
	journal = {Journal of Gastrointestinal Oncology},
	volume = {8},
	number = {4},
	year = {2017},
	keywords = {},
	abstract = {Background: There is a paucity of data on the impact of splenectomy on peri-operative outcomes after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC). We report the largest series to date which addresses this topic. 
Methods: Nine hundred and thirty six consecutive patients underwent CRS/HIPEC from 1996 to 2016 at a high-volume institution in Sydney, Australia. Of these, 418 (45%) underwent splenectomy. Peri-operative complications were graded according to the Clavien-Dindo Classi cation. The association of splenectomy with 19 peri-operative outcomes was assessed using univariate and multivariate analyses. 
Results: In-hospital mortality was 1.8%. Patients undergoing splenectomy had a higher disease burden (peritoneal cancer index ≥17) (71% vs. 22%, P},
	issn = {2219-679X},	url = {https://jgo.amegroups.org/article/view/14675}
}