@article{JGO17377,
author = {Everardo Jaime- Andrade and Leonardo S. Lino- Silva and Rosa A. Salcedo- Hernández and César Zepeda- Najar},
title = {Colorectal lymphoma in Mexico: clinico-pathological and survival analysis},
journal = {Journal of Gastrointestinal Oncology},
volume = {9},
number = {1},
year = {2017},
keywords = {},
abstract = {Background: Primary colorectal lymphomas (PCLs) are very rare. We analyze a series of PCL to establish an approximate frequency of the disease and their clinico-pathological characteristics.
Methods: A retrospective cross-sectional study in a third-level hospital from 2006–2016. Clinico-pathologic features of 18 cases are presented.
Results: PCL corresponded to 1.5% of malignant colorectal neoplasms. Ten cases presented in men, the median age was 57 years, diffuse large B-cell lymphoma (DLBCL) was the most common subtype (55.6%), 55.6% presented in cecum, 83.4% as unique polypoid tumor and the median size was 52.5 mm. The most prevalent presentation symptom was abdominal pain (61.1%). Six cases (33%) received initial surgery followed by chemotherapy, 7 cases (39%) received only chemotherapy, 2 cases received only surgery and 3 cases no-treatment. The 2-year disease specific survival was 62.7%. The only factors associated with improved survival in univariate analysis were use of surgery followed by chemotherapy (P=0.043) and HIV (P=0.043). On multivariate analysis none factor was an independent risk factor for decreased survival.
Conclusions: The improved overall survival rates in our series emphasize the importance of surgery followed systemic therapy in the treatment of this disease.},
issn = {2219-679X}, url = {https://jgo.amegroups.org/article/view/17377}
}