@article{JGO24694,
author = {Randa Tao and Bryan Ager and Shane Lloyd and Anna Torgeson and Michelle Denney and David Gaffney and Jordan Kharofa and Steven H. Lin and Albert C. Koong and Yoshimi Anzai and John M. Hoffman},
title = {Hypoxia imaging in upper gastrointestinal tumors and application to radiation therapy},
journal = {Journal of Gastrointestinal Oncology},
volume = {9},
number = {6},
year = {2018},
keywords = {},
abstract = {Survival for upper gastrointestinal tumors remains poor, likely in part due to treatment resistance associated with intratumoral hypoxia. In this review, we highlight advances in nuclear medicine imaging that allow for characterization of in vivo tumor hypoxia in esophageal, pancreatic, and liver cancers. Strategies for adaptive radiotherapy in upper gastrointestinal tumors are proposed that would apply information gained through hypoxia imaging to the creation of personalized radiotherapy treatment plans able to overcome hypoxia-induced treatment resistance, minimize treatment-related toxicities, and improve patient outcomes.},
issn = {2219-679X}, url = {https://jgo.amegroups.org/article/view/24694}
}