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Hypercalcemia from metastatic pancreatic neuroendocrine tumor secreting 1,25-dihydroxyvitamin D

   
@article{JGO2743,
	author = {Viola Zhu and Antonio de las Morenas and Milos Janicek and Kevan Hartshorn},
	title = {Hypercalcemia from metastatic pancreatic neuroendocrine tumor secreting 1,25-dihydroxyvitamin D},
	journal = {Journal of Gastrointestinal Oncology},
	volume = {5},
	number = {4},
	year = {2014},
	keywords = {},
	abstract = {Malignant hypercalcemia occurs in about 20-30% of patients with cancer, both solid tumors and hematologic malignancies. The secretion of parathyroid hormone-related protein (PTH-rP) is the most common cause and has been shown to be the etiology of hypercalcemia associated with neuroendocrine tumors. Here we report the case of a patient with metastatic pancreatic neuroendocrine tumor who developed hypercalcemia more than 4 years after the initial diagnosis as a result of secretion of 1,25-dihydroxyvitamin D, a mechanism only commonly seen in lymphomas. The successful control of the patient’s disease with capecitabine and temozolomide led to the alleviation of this paraneoplastic syndrome.},
	issn = {2219-679X},	url = {https://jgo.amegroups.org/article/view/2743}
}