@article{JGO2955,
author = {Thomas A. Heafner and Sean C. Glasgow},
title = {A critical review of the role of local excision in the treatment of early (T1 and T2) rectal tumors},
journal = {Journal of Gastrointestinal Oncology},
volume = {5},
number = {5},
year = {2014},
keywords = {},
abstract = {The optimal treatment of early (T1 and T2) rectal adenocarcinomas remains controversial. Local excision and radical resection with total mesorectal excision are the two surgical techniques for excising early rectal cancer. Each has their respective benefits, with local excision allowing for decreased operative morbidity and mortality while radical resection provides an oncologically complete treatment through lymphadenectomy. Local excision can be accomplished via transanal endoscopic microsurgery or transanal excision. There is no significant difference in the recurrence rates (21% vs. 33%) or overall survival (80% vs. 66%) between the two local excision modalities; however, transanal endoscopic microsurgery does allow for a higher rate of R0 resection. Current selection criteria for local excision include well to moderately differentiated tumors without high-risk features such as lymphovascular invasion, perineural invasion, or mucinous components. In addition, tumors should ideally be },
issn = {2219-679X}, url = {https://jgo.amegroups.org/article/view/2955}
}