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Outcomes of resected pancreatic cancer in patients age ≥70

  
@article{JGO4370,
	author = {Thomas J. Hayman and Tobin Strom and Gregory M. Springett and Lodovico Balducci and Sarah E. Hoffe and Kenneth L. Meredith and Pamela Hodul and Mokenge Malafa and Ravi Shridhar},
	title = {Outcomes of resected pancreatic cancer in patients age ≥70},
	journal = {Journal of Gastrointestinal Oncology},
	volume = {6},
	number = {5},
	year = {2015},
	keywords = {},
	abstract = {Objective: To determine outcomes of patients ≥70 years with resected pancreatic cancer. 
Methods: A study was conducted to identify pancreatic cancer patients ≥70 years who underwent surgery for pancreatic carcinoma from 2000 to 2012. Patients were excluded if they had neoadjuvant therapy. The primary endpoint was overall survival (OS). 
Results: We identified 112 patients with a median follow-up of surviving patients of 36 months. The median patient age was 77 years. The median and 5 year OS was 20.5 months and 19%, respectively. Univariate analysis (UVA) showed a significant correlation for increased mortality with N1 (P=0.03) as well as post-op CA 19-9 >90 (P90 (P=0.002), while adjuvant chemoradiation (P=0.04) was associated with decreased mortality. 
Conclusions: These data show that in patients ≥70, nodal status, post-op CA 19-9, and adjuvant chemoradiation, were associated with OS. The data suggests that outcomes of patients ≥70 years who undergo upfront surgical resection are not inferior to younger patients.},
	issn = {2219-679X},	url = {https://jgo.amegroups.org/article/view/4370}
}