Vol 17, No 1 (February 28, 2026): Journal of Gastrointestinal Oncology

Original Article

The association between adherence to elective nodal volume guidelines and reduced distant metastasis in esophageal and gastroesophageal junction cancer: a retrospective analysis of elective nodal irradiation
Jared Lyons, Garrett Harada, John Yeakel, Farshid Dayyani, Brian Smith, Shaun Daly, Ninh Nguyen, Harada Keshava, Suzanne Dufault, Caressa Hui, Alexandra Hotca, Steven Seyedin
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:1
.
 (28 February 2026) 
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Risk factors and prognostic implications of upper or middle mediastinal lymph nodes metastasis and recurrence in esophagogastric junction carcinoma
Shintaro Nozu, Takashi Fukuda, Shinichiro Shiomi, Daiji Oka
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:2
.
 (28 February 2026) 
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Identification and validation of an explainable machine learning model for early postoperative pulmonary complications after esophagectomy in patients with esophageal cancer
Feifei Liu, Zhibo Wang
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:3
.
 (28 February 2026) 
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Private equity acquisitions of hospitals and the changing landscape of care for patients with gastrointestinal cancer
Eshetu Worku, Zayed Rashid, Mujtaba Khalil, Selamawit Woldesenbet, Timothy M. Pawlik
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:4
.
 (28 February 2026) 
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Cadonilimab plus chemotherapy vs. PD-1 inhibitor plus chemotherapy as first-line treatment for advanced gastric or gastroesophageal junction cancer with PD-L1 combined positive score <5: a propensity-matched, retrospective cohort study
Duqin Zhao, Zhongyue Wu, Yihui Huang, Lei Zhang, Xing Yuan, Nannan Zhang, Qing Wei, Jingjing Li, Jieer Ying, Qi Xu
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:5
.
 (28 February 2026) 
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Training and validation of a nomogram for predicting synchronous distant organ metastasis in patients with very-early-onset colorectal cancer
Yajing Wen, Zhemin Li, Huilian Zhang, Jinyu Huang, Yuqin Zhang, Yi Ding, Jianbiao Xiao, Yaowei Zhang
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:6
.
 (28 February 2026) 
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Construction of taurine metabolism-related risk model and subtype identification in colorectal cancer to predict prognosis and immunological features
Qinghua Wang, Xiaoxiao Chen, Hongjuan Zheng, Jianfei Fu, Ying Yuan
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:7
.
 (28 February 2026) 
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Non-surgical management of malignant bowel obstruction: strategies and outcomes in inoperable patients
Tomas Escobar Gil, Pooja Viswanath, Stephanie Rosenberg, Mohammed A. Quazi, Valeria Hanson, Alan Ortega Macias, Amy Tarnower
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:8
.
 (28 February 2026) 
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A hybrid molecular-imaging model for high-accuracy early colorectal cancer diagnosis
Yong Zhao, Weirong Zeng
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:9
.
 (28 February 2026) 
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A nine-gene nicotine-metabolism signature predicts prognosis and characterizes the immune landscape in colon adenocarcinoma
Junliang Li, Junyi Zhang, Danning Wang, Jieyi Shen, Chong Shen, Weiqi Zeng, Jianwei Wang
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:10
.
 (28 February 2026) 
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Overstaging of the mesorectal fascia following neoadjuvant therapy and its impact on therapeutic management: a single-center retrospective cohort study of 506 mesorectal fascia positive patients
Xiao Huang, Tianan Guo, Huan Zhang, Yiwei Zeng, Dan Huang, Tong Tong, Ye Xu
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:11
.
 (28 February 2026) 
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ColoLDB: a machine learning-based predictive model for colorectal cancer using routine laboratory parameters
Xing Zhang, Xuedong Tong, Jiangtao Mou, Jun Liu, Chenxi Zhang, Hongyan Han, Kun Deng
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:12
.
 (28 February 2026) 
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Colon cancer cachexia remodels gut microbiota and metabolite profiles in a murine model
Ting Zou, Jingwei Zheng, Zhangyi Xie, Yan Hu, Xinxin Yang, Xiangyang Xue, Liting Lu, Xiaodong Chen, Sunzhong Mao, Mengyuan Niu
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:13
.
 (28 February 2026) 
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Comparable survival outcome with anti-EGFR therapy in any treatment line in left-sided metastatic colorectal cancer
Anita Archwamety, Charuwan Akewanlop, Krittiya Korphaisarn
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:14
.
 (28 February 2026) 
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Association of fruit and vegetable consumption with colorectal adenoma among adults in Korea: a cross-sectional study
Akinkunmi Paul Okekunle, Jiyoung Youn, Ji Hyun Song, Young Sun Kim, Sun Young Yang, Jung Eun Lee
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:15
.
 (28 February 2026) 
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Clinicopathological characteristics and prognosis of patients with mucinous adenocarcinoma originating from the left colon, right colon, or rectum: a nationwide retrospective study in China
Bingxu Liu, Haoqing He, Xu Guan, Peng Zhang, Benjia Liang, Yueming Sun, Minhao Yu, Shanglei Ning, Yifei Zhang, Yanfeng Lv, Yanwu Sun, Qi Sun, Lei Wang, Jiangang Liu, Meng Jiao, Yanlai Sun, Congqing Jiang, Xianghai Ren, Jun Li, Dongning Liu, Zhao Zhang, Zhibin Ye, Bin Ma, Guodong Yu, Wei Fu, Xiangheng Kong, Jingbo Chen, Changqing Jing, Guangyong Zhang, Hui Yang
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:16
.
 (28 February 2026) 
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CPNE3 promotes colorectal cancer progression by regulating KIF4-mediated autophagy
Chong Tang, Wu Teng, Yasu Jiang, Yongyou Wu
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:17
.
 (28 February 2026) 
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The EZH2-NEAT1 epigenetic axis promotes cuproptosis sensitivity and modulates cancer cell migration in colorectal cancer
Ruibing Li, Qiang Tao, Xijie Chen, Chuanyuan Liu, Huanmiao Zhan, Chong Wang, Xinyou Wang, Yijia Lin
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:18
.
 (28 February 2026) 
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Short- and long-term outcomes after laparoscopic and open liver resection for combined hepatocellular-cholangiocarcinoma patients: a propensity score-matched study
Xin Deng, Fei Liang, Bo-Wen Wang, Shuai Xu, Wei Gong
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:19
.
 (28 February 2026) 
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Separation of liver focal nodular hyperplasia (FNH) and liver malignant tumors by a combination of T2-weighted imaging signal and three diffusion magnetic resonance metrics of diffusion-derived vessel density, slow diffusion coefficient, and apparent diffusion coefficient
Cai-Ying Li, Cun-Jing Zheng, Xiao-Hui Duan, Jun Shen, Yì Xiáng J. Wáng
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:20
.
 (28 February 2026) 
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Barcelona Clinic Liver Cancer strategy adherence in hepatocellular carcinoma and its influence on long-term outcomes
Niklas Sarelin, Valtteri Kairaluoma, Minna Nortunen, Marjo Koskela, Juha Saarnio, Joonas H. Kauppila, Olli Helminen, Heikki Huhta
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:21
.
 (28 February 2026) 
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ΔSII-based nomogram for prognosis prediction after radical resection for hepatocellular carcinoma
Yang Zou, Min Jin, Ming Luo, Kai He
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:22
.
 (28 February 2026) 
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Hedyotis diffusa Willd suppresses hepatocellular carcinoma tumor-stromal interactions by inactivating cancer-associated hepatic stellate cells
Jing Chen, Tongnin Zhong, Xuemei Li, Yuxi Han, Jinglin Lai, Defeng Lei, Qirui Lin, Minghua Li, Zilong Yan
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:23
.
 (28 February 2026) 
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Clinical model for predicting overall survival outcomes in individuals with hepatocellular carcinoma: a retrospective cohort analysis
Maher Hendi, Ying-Ying Chen, Bin Zhang, Yi-Fan Wang, Xiu-Jun Cai
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:24
.
 (28 February 2026) 
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Global research trends and foci of ablation therapies for liver tumours: a scientometric study
Shu Dong, Chien-Shan Cheng, Lin Xie, Weijun Fan, Ping Liang, Zhiqiang Meng
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:25
.
 (28 February 2026) 
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FTSJ1-mediated IL1RN mRNA instability promotes inflammation-driven hepatocellular carcinoma
Shuya Jiang, Dongyang Ding, Yunxi Zu, Yan Liao, Tengjiao Wang, Jian Yu, Weiping Zhou, Shengxian Yuan
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:26
.
 (28 February 2026) 
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Development and internal validation of a predictive nomogram for early postoperative bacterial infections following liver transplantation in patients with hepatocellular carcinoma
Peng-Fei Cheng, Li He, Bin-Wei Duan, Gong-Ming Zhang, Feng Wu, Jin-Xi Wang, Guang-Ming Li
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:27
.
 (28 February 2026) 
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Identification of mitochondrial-related subtypes and development of a prognostic model for pancreatic ductal adenocarcinoma
Fen Zhang, Zijian Jiang, Yuan Gao, Desheng Wang, Shuqiang Yue
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:28
.
 (28 February 2026) 
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Real-world comparative effectiveness of FOLFIRINOX versus gemcitabine/nab-paclitaxel in metastatic pancreatic cancer: prognostic impact of metastatic site and burden in a Middle Eastern cohort
Wesal M. Eldehna, Fawzy Elbarbry, Rafat Abu Shakra, Shaimaa A. Elrasad, Zeinab A. Morsi, Shamel M. Soaida, Wael M. Wagdy, Abrar I. Aljohani, Ramy M. Abbas
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:29
.
 (28 February 2026) 
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Review Article

The APOBEC3 family: a narrative review of an alternative therapeutic agent for hepatitis B virus-induced hepatocellular carcinoma
Jing Miao, Meng Zhang, En Ren, Lan-Tian Huang, Kai-Feng He, Zhi-Gang Gao
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:30
.
 (28 February 2026) 
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Study Protocol

DAWN trial: a prospective, multicenter, single-arm phase II study of neoadjuvant disitamab vedotin (RC48) in combination with adebrelimab, apatinib, and S-1 for locally advanced HER2-positive gastric cancer
Yuting Ding, Hao Qian, Hongda Liu, Jiaguang Zhang, Xinyi Zhang, Jia Wei, Xiaofeng Chen, Hao Xu
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:31
.
 (28 February 2026) 
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Case Series

Partial splenic embolization plus antitumor therapy for treating patients with hepatocellular carcinoma and splenomegaly: a case series study
Benke Li, Bozhao Jiang, Xiaolei Pang, Min Ji
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:32
.
 (28 February 2026) 
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Case Report

A case report: Masson’s tumor (intravascular papillary endothelial hyperplasia) of the abdominal cavity
Yiran Ren, Xiangrong Yu
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:33
.
 (28 February 2026) 
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Editorial Commentary

Beyond LEAP-015: the ongoing challenge of vascular endothelial growth factor inhibition in gastric cancer
Oluseyi Abidoye, Mohamad Bassam Sonbol
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:34
.
 (28 February 2026) 
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Checkpoint inhibition in advanced biliary tract cancer: progress, limitations, and the search for biomarker-driven strategies
Elisa Giovannetti, Mafalda Angelica Rocco, Virginia Agnetti, Laiba Mariyam, Teresa Maria Assunta Fasciana, Ingrid Garajová
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:35
.
 (28 February 2026) 
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The role of chemoradiotherapy after induction in locally advanced pancreatic cancer: lessons learnt from CONKO-007
Christos Athanasiou, Sanjay Pandanaboyana
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:36
.
 (28 February 2026) 
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In search of the best perioperative treatment for gastroesophageal cancer: is there a role for antiangiogenesis?
Thierry Alcindor
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:37
.
 (28 February 2026) 
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Anlotinib and penpulimab in advanced hepatocellular carcinoma: a new contender emerges
Oluseyi Abidoye, Daniel Ahn
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:38
.
 (28 February 2026) 
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Regorafenib in refractory gastric cancer: modest median, meaningful milestone
Yukiya Narita, Kei Muro
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:39
.
 (28 February 2026) 
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Antiangiogenic therapy for advanced biliary tract cancers: promising or illusory?
Raphael Colle, David Malka
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:40
.
 (28 February 2026) 
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Development of systemic chemotherapy starting from comparison with best supportive care: commentary on the INTEGRATE IIa phase III study
Narikazu Boku
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:41
.
 (28 February 2026) 
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Bevacizumab in biliary tract cancer: a clinical catalyst in the era of chemo-immunotherapy?
Umair Mahmood, Umer Khan, Khurum Khan
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:42
.
 (28 February 2026) 
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Editorial

Biology before stage in advanced gastric cancer: converting to cure in biomarker-selected patients
Yassine Alami Idrissi, Alina Zatsepina, Anwaar Saeed
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:43
.
 (28 February 2026) 
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Retraction

Retraction: HMGB2 upregulation promotes the progression of hepatocellular carcinoma cells through the activation of ZEB1/vimentin axis
Editorial Office
Journal of Gastrointestinal Oncology  
2026;
17
(1)
:44
.
 (28 February 2026) 
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