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JGO 2025 Annual Report

Greetings from the editorial office of Journal of Gastrointestinal Oncology (JGO).

We’re glad to present the 2025 Annual Report of JGO. The newly released Impact Factor of JGO is 2.

We would like to extend our sincere gratitude to our editorial board members, reviewers, authors and readers. We wish you a happy, healthy and prosperous 2026 and we look forward to working with you to continue the success of JGO.

AME and Wolters Kluwer aim to expand access to global medical research through new collaboration

The agreement broadens the reach of nearly 50 Open Access titles, contributing globally to over 5,000 articles

October 2, 2025 — Wolters Kluwer Health announced a new collaboration with AME Publishing Company, an Open Access publisher specializing in medical journals and books, headquartered in Hong Kong, China.

New Impact Factor for Journal of Gastrointestinal Oncology: 2

We are pleased to announce that the Journal of Gastrointestinal Oncology (JGO) has attained its latest impact factor update for the 2024 citation year: 2.

Journal of Gastrointestinal Oncology 2024 CiteScore Released: 3.7

We are pleased to announce that the Journal of Gastrointestinal Oncology (JGO) has achieved its 2024 CiteScore: 3.7, ranking 81 out of 173 journals in the Gastroenterology category and 225 out of 415 journals in the Oncology category. This milestone underscores our ongoing commitment to publishing impactful research in the field.

Reviewer of the Month (2025)

In 2025, JGO reviewers continue to make outstanding contributions to the peer review process. They demonstrated professional effort and enthusiasm in their reviews and provided comments that genuinely help the authors to enhance their work.

Hereby, we would like to highlight some of our outstanding reviewers, with a brief interview of their thoughts and insights as a reviewer. Allow us to express our heartfelt gratitude for their tremendous effort and valuable contributions to the scientific process.

Interviews with Outstanding Authors (2025)

In 2025, many JGO authors make outstanding contributions to our journal. Their articles published with us have received very well feedback in the field and stimulate a lot of discussions and new insights among the peers.

Hereby, we would like to highlight some of our outstanding authors who have been making immense efforts in their research fields, with a brief interview of their unique perspective and insightful view as authors.

Journal of Gastrointestinal Oncology (JGO) is now a member of Committee on Publication Ethics (COPE)

Starting from July 2021, AME Publishing Company is formally recognized a publisher member of Committee on Publication Ethics (COPE) and over 60 AME-published journals become a member of Committee on Publication Ethics (COPE), as part of AME’s commitment to best practice in scholarly publishing. Journal of Gastrointestinal Oncology (JGO) is among the list of COPE membership.

Implementation of transparent peer review at Journal of Gastrointestinal Oncology (JGO)

Editorial office, Journal of Gastrointestinal Oncology

With a commitment to openness and accountability, and to increase the level of transparency throughout our peer review process, our editorial office has decided to implement a transparent peer review process as an option for all manuscripts submitted to JGO from June 11, 2020.

Editors’ Choice

Peering into the darkness of drug-induced thrombotic microangiopathy: complement, are you in there?

Conventional management of drug-induced thrombotic microangiopathies (DI-TMAs) is centered around drug cessation and supportive care. This can be quite troublesome since many of these offending medications are important antineoplastic or immunosuppressive drugs that may not have equivalent alternatives.

Editors’ Choice

Evolution of pancreatic surgery over time and effects of centralization—a single-center retrospective cohort study

Kaplan-Meier curves of long-term survival, stratified by time quartiles.

Editors’ Choice

Whole-genome sequencing of 20 cholangiocarcinoma cases reveals unique profiles in patients with cirrhosis and primary sclerosing cholangitis

Circos plots histograms demonstrating mutational burden, structural patterns and substitution base signatures. (A) A patient with MLH1 driven MMRd cholangiocarcinoma noting the burden of small indels. (B) A patient with a prior history of mantle cell lymphoma and evidence of signature 3 usually identifying with homologous recombination deficiency. (C) A patient with UC-PSC, a high TMB, and predominance of SBS17.

Editors’ Choice

An unusual paraesophageal and diaphragmatic SDHA-deficient gastrointestinal stromal tumor (GIST) metastases case report

Radiographic images. (A) Axial image demonstrating mediastinal metastatic lesions (tumor highlighted by red arrow). (B) Coronal image fully showing tumor extension from the diaphragm to subcarinal space (tumor highlighted by red arrow). (C) Satellite diaphragmatic mass (highlighted by red arrow).

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Vol 17, No 2 (April, 2026)

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Original Article

Predictive model based on folate receptor-positive circulating tumor cells in neoadjuvant immunochemotherapy for esophageal cancer

Huanrong Wang, Hua Bai, Dan Yang, Wenhui Wang, Fanfan Zhou, Meifeng Yin, Chen Yan, Yunxia Guo, Kai Li, Jizhi Zhao, Li Yang, Pu Yu, Ruijun Li

Journal of Gastrointestinal Oncology

2026;

(2)

:45

(30 April 2026)

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Neoadjuvant adebrelimab combined with triplet chemotherapy for locally advanced resectable adenocarcinoma of esophagogastric junction: a prospective, single-arm, phase II feasibility and safety study

Jinqiang Liu, Rui Zhang, Wei Zhou, Zhenshun Li, Guangwen Zhang, Li Yang, Aqiang Fan, Shushang Liu, Yan Miao, Hao Sun, Liu Hong, Mian Wang

Journal of Gastrointestinal Oncology

2026;

(2)

:46

(30 April 2026)

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The prevalence of gastric intestinal metaplasia in the Saudi population: a single-tertiary center retrospective study

Emad S. Aljahdli, Murad Aljiffry, Rana Y. Bokhary, Najla Alghanmi, Ashraf A. Maghrabi, Mohammed Alharthi, Ghassan M. Malibari, Bashaer A. Alasmari, Wedad S. Mhalawi, Baraa E. Abuzinadah, Hamza H. Bali, Sulaiman Hanbazazah, Hassan Atalla, Eyad Gadour

Journal of Gastrointestinal Oncology

2026;

(2)

:47

(30 April 2026)

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Prognostic impact of low absolute skeletal muscle mass 6 months after gastrectomy for gastric cancer: a retrospective cohort study

Shunsuke Yamagishi, Yasuhiro Okumura, Kosuke Narumiya, Takaharu Kawai, Masahito Ikarashi, Shu Inagaki, Masataka Shindate, Hayato Abe, Yusuke Mitsuka, Nao Yoshida, Osamu Aramaki, Yukiyasu Okamura

Journal of Gastrointestinal Oncology

2026;

(2)

:48

(30 April 2026)

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Diagnostic value of mini-probe endoscopic ultrasound in preoperative tumor nodal (TN) staging of gastric cancer and analysis of factors influencing T-staging accuracy

Yanli Cheng, Hongwei Guo, Yali Wang, Yiyan Long, Shuai Luo, Zepeng Xin, Yan Weng

Journal of Gastrointestinal Oncology

2026;

(2)

:49

(30 April 2026)

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Transcatheter arterial embolization with n-butyl cyanoacrylate versus gelatin sponge particles for gastric cancer-related upper gastrointestinal bleeding: a comparison of efficacy and safety

Deyu He, Liming Shao, Yixing Xie, Xiaolong Zhao, Zhaolong Zhang, Rui Xu, Chengjian Sun, Guoping Liu

Journal of Gastrointestinal Oncology

2026;

(2)

:50

(30 April 2026)

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Postoperative frailty among elderly patients undergoing radical surgery for gastrointestinal tumors and its relationship with prognosis

Yunsong Li, Chunwei Peng, Bingbing Zou

Journal of Gastrointestinal Oncology

2026;

(2)

:51

(30 April 2026)

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Molecular characteristics and metastatic mechanism of patients diagnosed with Krukenberg tumor from gastric cancer

Xiaoye Liu, Xi Wang, Mingwei Li, Xiaoxue Ma, Huina Wang, Jiayue Qin, Zhi Zheng, Rui Xu, Xiaobao Yang, Jie Yin, Jun Zhang

Journal of Gastrointestinal Oncology

2026;

(2)

:52

(30 April 2026)

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Retrospective study on clinical outcomes and safety evaluation of da Vinci robot-assisted laparoscopy and endoscopic cooperative for small gastric stromal tumors resection: preliminary single-center experience

Jiawei Zhang, Hongzhi Wang, Hong Fang, Yanhong Liu, Jia Zhao, Chuntao Wang, Peng Song, Lei Cao

Journal of Gastrointestinal Oncology

2026;

(2)

:53

(30 April 2026)

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The impact of ulinastatin on postoperative clinical outcomes in patients with gastric cancer: a retrospective cohort analysis

Lihong Chen, Zhizhong Xiong, Saddam Ahmed Mohamed, Wenyuan Deng, Dayin Huang, Zhijie Wu, Yafen Chen, Lei Lian, Qiongyu Hu

Journal of Gastrointestinal Oncology

2026;

(2)

:54

(30 April 2026)

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Comparison of the efficacy and safety of single-incision versus multi-port laparoscopic D2 lymphadenectomy for locally advanced gastric cancer: a systematic review and meta-analysis

Ruijie Lin, Shoujiang Wei

Journal of Gastrointestinal Oncology

2026;

(2)

:55

(30 April 2026)

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Development and external validation of a prognostic nomogram for cancer-specific survival in elderly patients with early-stage gastric cancer

Yu-Xi Cheng, Wei Tao, Hao Liu, Guo-Hao Wu

Journal of Gastrointestinal Oncology

2026;

(2)

:56

(30 April 2026)

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Identification of immunogenic cell death-related prognostic genes in gastric cancer

Qian Wan, Ling Zhang, Xia Zheng, Jun Qian

Journal of Gastrointestinal Oncology

2026;

(2)

:57

(30 April 2026)

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Opportunistic CT screening for osteosarcopenia predicts reduced overall survival in patients with gastric cancer: a retrospective cohort study

Zijie Lin, Bo Wen, Daolai Huang, Wenjie Fang, Weiming Ou, Yaodong Song, Jiahui Liu, Xiangzhong Yang, Jun Lan, Xianghua Wu

Journal of Gastrointestinal Oncology

2026;

(2)

:58

(30 April 2026)

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Patterns of recurrence and outcomes of poor responders to neoadjuvant long-course chemoradiotherapy for rectal cancer

Yufei Yang, Dakui Luo, Weiji Ding, Qingguo Li, Xinxiang Li

Journal of Gastrointestinal Oncology

2026;

(2)

:59

(30 April 2026)

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Identification of an autophagy-related prognostic signature and validation of WDR45 in colorectal cancer

Cuiying Qin, Youwu He, Wenling Wu, Binliang Gan, Xinning Luo, Xianjie Feng, Ganlu Deng

Journal of Gastrointestinal Oncology

2026;

(2)

:60

(30 April 2026)

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KRAS mutation subtypes refine prognostic stratification in colorectal cancer: a retrospective cohort study

Xin Li, Zhen-Ya Yang, Ning Xu, Jun Yang

Journal of Gastrointestinal Oncology

2026;

(2)

:61

(30 April 2026)

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Development and validation of manganese metabolism-related genes prognostic model in colorectal cancer and its immunological characteristics

Pei Wu, Yuwei Zhang

Journal of Gastrointestinal Oncology

2026;

(2)

:62

(30 April 2026)

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Intratumoral PKM2 expression predicts benefit from adjuvant FOLFOX in stage II–III colorectal cancer

Eonwoo Shin, Hyo Sang Lee, Dae-Woon Eom, Jae Young Kwak, Kwan Mo Yang, Ho-Suk Oh, Sehee Kim, Chang Sik Yu

Journal of Gastrointestinal Oncology

2026;

(2)

:63

(30 April 2026)

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Assessment of colorectal cancer recurrence risk following solid organ transplantation

David B. Meyer, Angela Gifford, Taylor Bradley, Thanh J. Nguyen, Valerie Lee, Katherine Bever, Ana De Jesus-Acosta, Daniel Laheru, Dung T. Le, Daniel C. Brennan, Brad C. Astor, Jacqueline Garonzik Wang, Eric S. Christenson

Journal of Gastrointestinal Oncology

2026;

(2)

:64

(30 April 2026)

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CCL5 promotes colon cancer progression via PI3K/AKT signaling and is negatively regulated by STAT1

Xinfeng Zhang, Xiaoli Zhang, Xu Luo, Yan Tian, Huayou Luo

Journal of Gastrointestinal Oncology

2026;

(2)

:65

(30 April 2026)

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Molecular subtyping and prognostic model construction based on endosome-related genes in colorectal cancer

Xiao Huang, Jie Yang

Journal of Gastrointestinal Oncology

2026;

(2)

:66

(30 April 2026)

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No survival benefit from adjuvant chemotherapy in high-risk stage II small intestinal adenocarcinoma after surgery: a population-based long-term survival analysis

Zhigang Yang, Zhengqiang Xiong, Hailin Huang, Yanyan Zhang

Journal of Gastrointestinal Oncology

2026;

(2)

:67

(30 April 2026)

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Transarterial embolization combined with octreotide long-acting release in treating rectal neuroendocrine tumor liver metastases: a single-institutional experience

Qing Zhao, Cui-Xian Li, Luo-Hai Chen, Yun Liang, Wei Tang, Jun-Yan Xu, Jie Chen, Li-Chao Xu

Journal of Gastrointestinal Oncology

2026;

(2)

:68

(30 April 2026)

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Single-cell transcriptome analysis identifies neutrophil-related prognostic signatures in hepatocellular carcinoma

Shuting Yang, Dan Wang, Jinghui Du

Journal of Gastrointestinal Oncology

2026;

(2)

:69

(30 April 2026)

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TRNP1 regulates tumorigenesis and enhances immunotherapy response via c-Kit/STAT3 signaling in hepatocellular carcinoma

Jian Hu, Ning Zhang, Yanfen Ma, Nian Zhou, Xiaoqian Wang, Kaige Zhang, Qian Wu, Xiaoqin Wang, Feifei Mao

Journal of Gastrointestinal Oncology

2026;

(2)

:70

(30 April 2026)

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Perioperative clinicopathologic model for predicting 12-month early recurrence after curative hepatectomy in hepatocellular carcinoma

Lu Zhang, Qiyu Lu, Xiaoyan Wang

Journal of Gastrointestinal Oncology

2026;

(2)

:71

(30 April 2026)

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Association of serum lactate dehydrogenase levels with the severity of microvascular invasion in hepatocellular carcinoma: a retrospective cross-sectional study

Yuejiao Fan, Guangqin Xiao, Jianli Hu

Journal of Gastrointestinal Oncology

2026;

(2)

:72

(30 April 2026)

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An exploratory nomogram model with ¹⁸F-FDG PET/CT metabolic parameters for predicting high-risk status of microvascular invasion in hepatocellular carcinoma patients prior to liver transplantation

Shichang Li, Ai’nan Guo, Xue Wang, Ying Tian, Fang Zhang, Lingge Wei, Peng Fu

Journal of Gastrointestinal Oncology

2026;

(2)

:73

(30 April 2026)

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Impact of tumor mutation burden on the prognosis of patients with unresectable hepatocellular carcinoma undergoing transcatheter arterial chemoembolization combined with immunotherapy and anti-angiogenic drugs

Xiao-Wang Huang, De-Jie Wang, Bang-Zhun Cai

Journal of Gastrointestinal Oncology

2026;

(2)

:74

(30 April 2026)

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Prognostic genes in hepatocellular carcinoma and their function: an analysis integrating high-throughput-based spatial transcriptomics and single-cell RNA-sequencing

Yumei Zhang, Yu Yao, Zongcai Yan, Meiling He, Yingjie Tang, Zhiming Zhang

Journal of Gastrointestinal Oncology

2026;

(2)

:75

(30 April 2026)

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PD-1 inhibitors combined with tyrosine kinase inhibitors for conversion therapy in patients with unresectable hepatocellular carcinoma: a retrospective cohort study

Gang Liu, Chengxiang Guo, Xiaoli Li, Zhe Lv, Jiali Du, Liansheng Gong

Journal of Gastrointestinal Oncology

2026;

(2)

:76

(30 April 2026)

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Development and validation of a model for predicting short-term complications after hepatectomy in patients with primary liver cancer

Ruo-Chen Wang, Wen-Yang Niu, Xiao-Liang Lu, Ze-Fa Lu, Yi Qian

Journal of Gastrointestinal Oncology

2026;

(2)

:77

(30 April 2026)

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Temporal change in liver function after stereotactic body radiation therapy for hepatocellular carcinoma

Daniel Mills, Michael Potter, Steven Bollipo, Liam Shun, Jaw Tronidjaja, Swetha Sridharan, Mahesh Kumar, Jarad Martin, Yuvnik Trada

Journal of Gastrointestinal Oncology

2026;

(2)

:78

(30 April 2026)

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A novel deep learning and radiomics approach based on DCE-MRI for predicting the P53 mutation status in hepatocellular carcinoma

Jingfei Weng, Yuqing He, Qihu Zeng, Dinghua Yao, Hanzhong Zhou, Bo Li, Chun Yang, Bin Yang

Journal of Gastrointestinal Oncology

2026;

(2)

:79

(30 April 2026)

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Peripheral regulatory T cells trajectory predicts progression-free survival in hepatocellular carcinoma patients during on-demand transarterial chemoembolization using joint model: a prospective study

Qiyang Chen, Siwei Yang, Jian Li

Journal of Gastrointestinal Oncology

2026;

(2)

:80

(30 April 2026)

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PD-1/PD-L1 expression and predictive value of efficacy in hepatocellular carcinoma patients with anti-PD-1 therapy: a real-world study

Huili Wu, Hui Liu, Yang Wang, Lin Sun, Mei Liu, Jun Lv

Journal of Gastrointestinal Oncology

2026;

(2)

:81

(30 April 2026)

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Indeterminate nodule-like arterial phase hyperenhancement in the liver on CT: differentiation of hepatocellular carcinomas from vascular pseudolesions using a CT radiomics approach

Sungeun Park, Ijin Joo, Jae Hyun Kim, Sewoo Kim, Jin Sol Choi, Jeong Min Lee

Journal of Gastrointestinal Oncology

2026;

(2)

:82

(30 April 2026)

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Association between primary tumor resection and survival in metastatic intrahepatic cholangiocarcinoma: a retrospective cohort study based on the SEER database

Xiao Yang, Ruonan Xu, Zhe Xu, Yaxin Wu, Kai Liu

Journal of Gastrointestinal Oncology

2026;

(2)

:83

(30 April 2026)

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Multi-scale deep learning models based on MRI for predicting pathological differentiation and evaluating its association with recurrence-free survival in hepatocellular carcinoma: an explainable machine learning study

Xue-Yong Zuo, Hai-Feng Liu

Journal of Gastrointestinal Oncology

2026;

(2)

:84

(30 April 2026)

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Daily increment of residual liver regeneration (DIRER) predicts tumor recurrence and mortality after radical hepatectomy for hepatocellular carcinoma

Jin Qian, Kehan Ye, Feiyang Ye, Shutong Zhang, Minghao Zou, Yangchi Zhou, Susu Luo, Ningyang Jia, Fuchen Liu, Hui Liu

Journal of Gastrointestinal Oncology

2026;

(2)

:85

(30 April 2026)

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Silencing OTUB1 induces pyroptosis to inhibit the growth of liver cancer HepG2 cells via the NLRP3/caspase/GSDM signaling pathway

Wen-Qi Chu, Rui-Ling Xu, Ming-Na Liu, Chen Hu, Xin-Yu Geng, Jing Liu, Chengqian Lv, Yan Li, Jing Wang, Xin-Hong Wang

Journal of Gastrointestinal Oncology

2026;

(2)

:86

(30 April 2026)

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Targeting AKR1C1 overcomes lenvatinib resistance in hepatocellular carcinoma through the STAT3-ABC transporters pathway

Yue Zhang, Lu Zheng, An-Qiang Feng, Cheng-Wen Zhao, Xin-Wei Xu, Han Wu, Yang Yu, Feng Gu, Yong-Qiang Chen

Journal of Gastrointestinal Oncology

2026;

(2)

:87

(30 April 2026)

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Multi-institutional care is associated with improved survival in biliary tract cancer

Trisha Lal, Jay Han, Natalie N. Chakraborty, Kai Zhao, Amit Mahipal, Christopher Towe, John B. Ammori, Richard S. Hoehn

Journal of Gastrointestinal Oncology

2026;

(2)

:88

(30 April 2026)

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Development and validation of machine learning models integrating spectral computed tomography-derived three-dimensional quantitative parameters for predicting histopathological grade in pancreatic ductal adenocarcinoma

Zuhua Song, Zongwen Li, Xinwei Wang, Jie Huang, Yuwei Chen, Xiaodi Zhang, Zhuoyue Tang

Journal of Gastrointestinal Oncology

2026;

(2)

:89

(30 April 2026)

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A biomarker-integrated nomogram for predicting postoperative pancreatic fistula in low- to intermediate-risk patients after pancreaticoduodenectomy

Saisai Zhu, Yixuan Zhang, Yifei Yang, Xiaodong Shan, Zhen Wang, Huansong Li, Xuehui Chu

Journal of Gastrointestinal Oncology

2026;

(2)

:90

(30 April 2026)

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Impact of preoperative body weight on short-term and long-term prognosis after pancreatic resection for pancreatic ductal adenocarcinoma: a multicenter study

Judong Li, Ting Niu, Ligang Shi, Xiaowei Deng, Xunan Mao, Guang Yang, Xing Liang, Meng Ji, Liang Tang, Danlei Chen, Anan Liu, Xinliang Lv, Lijun Hu, Xiaoyong Wang, Wei Wu, Chenghao Shao

Journal of Gastrointestinal Oncology

2026;

(2)

:91

(30 April 2026)

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A TRPM4-associated necrotic cell death signature for prognostic stratification in pancreatic cancer

Qingchun Li, Yong Zhou, Anding Wu, Yun Liang

Journal of Gastrointestinal Oncology

2026;

(2)

:92

(30 April 2026)

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Single-nucleus RNA sequencing reveals the effects of key regulators on human pancreatic adenocarcinoma and its tumor microenvironment

Xin Yan, Jing Zhao, Jing Yan, Gang Wu, Ranxing Yan, Liang Chen, Shirui Luo, Jiawu Liu, Xianghui Hou, Zhiyong Yang, Qian Zhu

Journal of Gastrointestinal Oncology

2026;

(2)

:93

(30 April 2026)

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Neoadjuvant radiotherapy after chemotherapy does not improve surgical or survival outcomes in borderline resectable pancreatic cancer

Larissa Garcia, Guilherme Rossato, Eduarda Montiel, Angelo Brito, Rodrigo Taboada, Alessandro Diniz, Heber Salvador, Silvio Torres, André Godoy, Dante Altenfenlder, Ricardo Fogaroli, Felipe Coimbra, Tiago Felismino

Journal of Gastrointestinal Oncology

2026;

(2)

:94

(30 April 2026)

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Review Article

A systematic review of artificial intelligence and machine learning for gut microbiome-based CRC screening

Mythri Chittilla, Priyanka Nagdev

Journal of Gastrointestinal Oncology

2026;

(2)

:95

(30 April 2026)

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Multimodal data-driven prediction of postoperative recurrence and survival in hepatocellular carcinoma: a narrative review

Ping Zhang, Xurui Kang, Yunzhang Cheng, Yun Feng, Yilin Wang

Journal of Gastrointestinal Oncology

2026;

(2)

:96

(30 April 2026)

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Risk factors for exclusive lung metastasis in colorectal cancer: a comprehensive narrative review

Zijun Zhou, Jianping Zhou, Fang Li

Journal of Gastrointestinal Oncology

2026;

(2)

:97

(30 April 2026)

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Advances in mitophagy research in hepatocellular carcinoma: mechanisms and therapeutic implications

Qinyu Guo, Hang Wang, Lei Zhu, Hongsong Deng, Zhongyong Jiang

Journal of Gastrointestinal Oncology

2026;

(2)

:98

(30 April 2026)

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Case Report

A case report of rectal squamous cell carcinoma following radiation therapy for prostate cancer: a management dilemma

Steve Oguguo Nwokeocha, Jasvindar Kumar, Rajat Soni, Shahin Shah, Anush V. Patel

Journal of Gastrointestinal Oncology

2026;

(2)

:99

(30 April 2026)

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Diagnostic challenges in gastrointestinal stromal tumors: a case report of concurrent gastrointestinal stromal tumor, lymphangioma, and solid pseudopapillary neoplasm of the pancreas

Alexandra M. Gustafson, Shruthi R. Perati, Evsen A. Arikan, Wanrun Lin, Audra A. Satterwhite, Stephanie N. Canady, Diane S. Ahn, Molly A. Sullivan, Stacy R. Joyce, Martha Quezado, Jeremy L. Davis, Andrew M. Blakely

Journal of Gastrointestinal Oncology

2026;

(2)

:100

(30 April 2026)

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Brain metastasis from KRAS wild-type pancreatic cancer and organoid correlates: a case report

Fatim M. Kouassi, Hardik Patel, Elias-Ramzey Karnoub, Caitlin F. Tsang, Julien Hohenleitner, Olca Basturk, Deepthi Budagavi, Madonna Moza, Fiyinfolu Balogun, Amber N. Habowski, David A. Tuveson, Kenneth H. Yu

Journal of Gastrointestinal Oncology

2026;

(2)

:101

(30 April 2026)

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Gastric lymphoma presenting with predominant pancreatitis and cranial neuropathy: a rare clinical presentation—a case report

Chao Li, Wen-Jing Yu, Gui-Bin Yang

Journal of Gastrointestinal Oncology

2026;

(2)

:102

(30 April 2026)

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A case report of gastroesophageal adenocarcinoma with yolk sac tumor differentiation in a pregnant patient

Rachel Patel, Alisha Hossain, Hiral Shah, Maged Khalil, Roberto Fratamico

Journal of Gastrointestinal Oncology

2026;

(2)

:103

(30 April 2026)

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Letter to the Editor

The underestimated global burden and projections of early-onset stomach and early-onset esophageal cancers

Manas Pustake

Journal of Gastrointestinal Oncology

2026;

(2)

:104

(30 April 2026)

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Impact of maintenance therapy with fluoropyrimidines in advanced esophageal-gastric adenocarcinoma: a critical review

Hafsa Naveed, Maria Feroz

Journal of Gastrointestinal Oncology

2026;

(2)

:105

(30 April 2026)

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Methodological clarifications on maintenance fluoropyrimidines in advanced esophagogastric adenocarcinoma: a real-world Mexican cohort

Abdel Karim Dip Borunda, Alberto Pimentel Rentería, Rafael Medrano Guzmán, Lizbeth Enríquez Román, Ana Elena Martin Aguilar, Rocío Grajales Álvarez, María Teresa De Jesús Cervantes Diaz

Journal of Gastrointestinal Oncology

2026;

(2)

:106

(30 April 2026)

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Fruquintinib in refractory metastatic colorectal cancer: separating randomized trial evidence from observational data

George Koulaouzidis, Anastasios Koulaouzidis, Wojciech Marlicz

Journal of Gastrointestinal Oncology

2026;

(2)

:107

(30 April 2026)

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Interpreting the evidence base for fruquintinib in refractory metastatic colorectal cancer

Jahnavi Udaikumar, Aasma Shaukat

Journal of Gastrointestinal Oncology

2026;

(2)

:108

(30 April 2026)

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Editorial Commentary

Biomarker-guided immuno-angiogenic therapy in biliary tract cancer: insights from IMbrave151

Christophe Cisarovsky, Ian Chau

Journal of Gastrointestinal Oncology

2026;

(2)

:109

(30 April 2026)

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Personalised neoadjuvant therapy, based on tumour characteristics and patient choice, is the best way forward in rectal cancer

Tarik Sammour

Journal of Gastrointestinal Oncology

2026;

(2)

:110

(30 April 2026)

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Is FOLFIRINOX more effective than gemcitabine plus nab-paclitaxel in pancreatic adenocarcinoma? A Decade of Debate! A commentary on the GENERATE, JCOG1611: a randomized, open-label, phase II/III trial

Hani M. Babiker

Journal of Gastrointestinal Oncology

2026;

(2)

:111

(30 April 2026)

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Emerging mechanisms of kinase inhibitor escape and clinical implications of ponatinib in advanced gastrointestinal stromal tumor

Santosh Shenoy

Journal of Gastrointestinal Oncology

2026;

(2)

:112

(30 April 2026)

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When precision medicine meets human behavior: limits of artificial intelligence in predicting imatinib adherence

Tatsuo Kanda

Journal of Gastrointestinal Oncology

2026;

(2)

:113

(30 April 2026)

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Anlotinib plus penpulimab: a new contender in first-line therapy for unresectable hepatocellular carcinoma

Atsushi Ono, C. Nelson Hayes, Tomokazu Kawaoka, Masataka Tsuge, Shiro Oka

Journal of Gastrointestinal Oncology

2026;

(2)

:114

(30 April 2026)

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Muscling in on body surface area to reduce oxaliplatin-induced peripheral neuropathy in colon cancer

Justin C. Brown

Journal of Gastrointestinal Oncology

2026;

(2)

:115

(30 April 2026)

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Clearing the bar: adding anti-VEGF therapy to chemoimmunotherapy for biliary tract cancer

Gentry King, Vaibhav Sahai

Journal of Gastrointestinal Oncology

2026;

(2)

:116

(30 April 2026)

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Editorial

Maximizing the “toolbox” for patients with initially unresectable colorectal liver metastases: have liver mets “met” their match?

Shannon N. Radomski, Linda Ye, Christopher Shubert, Eric S. Christenson

Journal of Gastrointestinal Oncology

2026;

(2)

:117

(30 April 2026)

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The 12-node rule in irradiated rectal cancer: time for reappraisal?

Da Wei Thong, Mary Theophilus

Journal of Gastrointestinal Oncology

2026;

(2)

:118

(30 April 2026)

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Beyond drug toxicity: the hidden burden of financial toxicity in hepatocellular carcinoma

Leonardo G. Da Fonseca

Journal of Gastrointestinal Oncology

2026;

(2)

:119

(30 April 2026)

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Gastrointestinal malignancies in pregnancy: practical considerations

Clare Anderson, Al B. Benson

Journal of Gastrointestinal Oncology

2026;

(2)

:120

(30 April 2026)

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Intrahepatic cholangiocarcinoma: the equity gap in one of the most lethal cancers

Mosunmoluwa Oyenuga, Olumide B. Gbolahan

Journal of Gastrointestinal Oncology

2026;

(2)

:121

(30 April 2026)

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Adjuvant chemotherapy in elderly colon cancer patients: when less may be more

Cody Eslinger, Mohamad Bassam Sonbol

Journal of Gastrointestinal Oncology

2026;

(2)

:122

(30 April 2026)

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Sarcopenia in esophageal cancer: from passive prognostic marker to active treatment target

Jin-Soo Park, Jerome M. Laurence, Steven Leibman, Gregory L. Falk, Garett Smith, Charbel Sandroussi

Journal of Gastrointestinal Oncology

2026;

(2)

:123

(30 April 2026)

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Return on investment, return of risk: private equity in gastrointestinal cancer care

Trisha Lal, Amrita Mukunda, Richard S. Hoehn

Journal of Gastrointestinal Oncology

2026;

(2)

:124

(30 April 2026)

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Tumor necrosis as a key refinement of risk stratification in gastric gastrointestinal stromal tumors

Masaya Iwamuro

Journal of Gastrointestinal Oncology

2026;

(2)

:125

(30 April 2026)

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Survival outcomes in early gastric cancer: evidence from SEER-based population studies

Hiroki Tanabe, Takao Sarashina, Yusuke Mizukami, Mikihiro Fujiya

Journal of Gastrointestinal Oncology

2026;

(2)

:126

(30 April 2026)

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Spontaneous rupture of hepatocellular carcinoma: mechanobiology, rescue, and oncologic control

Jingrong Yu, Vishal G. Shelat

Journal of Gastrointestinal Oncology

2026;

(2)

:127

(30 April 2026)

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From waste to wealth: malignant ascites-derived organoids as a compass for precision therapy in advanced gastrointestinal cancers

Koji Takahashi

Journal of Gastrointestinal Oncology

2026;

(2)

:128

(30 April 2026)

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Erratum

Erratum: Efficacy and safety of dose adjustment for fruquintinib in the third-line treatment of metastatic colorectal cancer: a retrospective study with real-world settings

Editorial Office

Journal of Gastrointestinal Oncology

2026;

(2)

:129

(30 April 2026)

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Retraction

Retraction: Interfering HMGB3 release from cancer-associated fibroblasts by miR-200b represses chemoresistance and epithelial-mesenchymal transition of gastric cancer cells

Yanzhuang Ke, Jieying Mai, Zhendong Liu, Yuyang Xu, Chunyi Zhao, Baochun Wang

Journal of Gastrointestinal Oncology

2026;

(2)

:130

(30 April 2026)

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Review Article

Colorectal carcinoma: Pathologic aspects

Matthew Fleming, Sreelakshmi Ravula, Sergei F. Tatishchev, Hanlin L. Wang

Published online: 01 September 2012

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Review Article

HDR brachytherapy for anal cancer

Peter Niehoff, Gyoergy Kovács

Published online: 30 June 2014

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Review Article

Gastric cancer: Classification, histology and application of molecular pathology

Bing Hu, Nassim El Hajj, Scott Sittler, Nancy Lammert, Robert Barnes, Aurelia Meloni-Ehrig

Published online: 01 September 2012

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Original Article

The clinical utility of serum CA 19-9 in the diagnosis, prognosis and management of pancreatic adenocarcinoma: An evidence based appraisal

Umashankar K Ballehaninna, Ronald S Chamberlain

Published online: 07 June 2012

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Review Article

Immunohistochemical features of the gastrointestinal tract tumors

Hannah H. Wong, Peiguo Chu

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Review Article

Postoperative management after hepatic resection

Lindsay J. Wrighton, Karen R. O’Bosky, Jukes P. Namm, Maheswari Senthil

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Change in CA 19-9 levels after chemoradiotherapy predicts survival in patients with locally advanced unresectable pancreatic cancer

Gary Y. Yang, Nadia K. Malik, Rameela Chandrasekhar, Wen-Wee Ma, Leayn Flaherty, Renuka Iyer, Boris Kuvshinoff, John Gibbs, Gregory Wilding, Graham Warren, Kilian Salerno May

Published online: 26 December 2013

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Assessment of clinical benefit and quality of life in patients undergoing cytoreduction and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for management of peritoneal metastases

Yue Zhu, Nader Hanna, Cherif Boutros, H. Richard Alexander, Jr.

Published online: 22 March 2013

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Case Report

Effectiveness of radiation therapy in GIST: A case report

Joshua Halpern, Yong-June Kim, Rumana Sultana, Gina Villani

Published online: 07 June 2012

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Original Article

Outcome of head compared to body and tail pancreatic cancer: a systematic review and meta-analysis of 93 studies

Gianluca Tomasello, Michele Ghidini, Antonio Costanzo, Antonio Ghidini, Alessandro Russo, Sandro Barni, Rodolfo Passalacqua, Fausto Petrelli

Published online: 08 April 2019

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Original Article

Association of Technetium99m MAG-3 renal scintigraphy with change in creatinine clearance following chemoradiation to the abdomen in patients with gastrointestinal malignancies

Kilian Salerno May, Gary Y Yang, Nikhil I Khushalani, Rameela Chandrasekhar, Gregory E Wilding, Leayn Flaherty, Harish K Malhotra, Richard C Russo, John C Warner, Johnny C Yap, Renuka V Iyer, Chukwumere E Nwogu, Saikrishna S Yendamuri, John F Gibbs, Hector R Nava, Dominick Lamonica, Charles R Thomas

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Case Report

The clinical utility of normal range carbohydrate antigen 19-9 level as a surrogate marker in evaluating response to treatment in pancreatic cancer—a report of two cases

Humaid O. Al-Shamsi, Mohammed Alzahrani, Robert A. Wolff

Published online: 01 June 2016

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Review Article

Diet and supplements and their impact on colorectal cancer

Marinos Pericleous, Dalvinder Mandair, Martyn E. Caplin

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Case Report

A curious discourse of Krukenberg tumor: a case report

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Case Report

Pulmonary metastases in pancreatic cancer, is there a survival influence?

Ayham Deeb, Sulsal-Ul Haque, Olugbenga Olowokure

Published online: 01 June 2015

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Review Article

Hepatocellular carcinoma (HCC): beyond sorafenib—chemotherapy

Dae Won Kim, Chetasi Talati, Richard Kim

Published online: 18 April 2017

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Clinical presentation, diagnosis, classification and management of peritoneal mesothelioma: a review

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Published online: 19 October 2017

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Original Articles

Evaluation of phosphatidylinositol-3-kinase catalytic subunit (PIK3CA) and epidermal growth factor receptor (EGFR) gene mutations in pancreaticobiliary adenocarcinoma

Guy A. Weiss, Michael Rossi, Nikhil Khushalani, Ken Lo, John F. Gibbs, Anubha Bharthuar, John K. Cowell, Renuka Iyer

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Imaging preoperatively for pancreatic adenocarcinoma

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Bax expression is a candidate prognostic and predictive marker of colorectal cancer

Venkat R Katkoori, Catalina Suarez-Cuervo, Chandrakumar Shanmugam, Nirag C Jhala, Tom Callens, Ludwine Messiaen, James Posey III, Harvey L Bumpers, Sreelatha Meleth, William E Grizzle, Upender Manne

Survival of metastatic gastric cancer: Significance of age, sex and race/ethnicity

Dongyun Yang, Andrew Hendifar, Cosima Lenz, Kayo Togawa, Felicitas Lenz, Georg Lurje, Alexandra Pohl, Thomas Winder, Yan Ning, Susan Groshen, Heinz-Josef Lenz

The influence of radiation therapy dose escalation on overall survival in unresectable pancreatic adenocarcinoma

William A. Hall, Lauren E. Colbert, Dana Nickleach, Jeffrey Switchenko, Yuan Liu, Theresa Gillespie, Joseph Lipscomb, Claire Hardy, David A. Kooby, Roshan S. Prabhu, John Kauh, Jerome C. Landry

Overall survival analysis of neoadjuvant chemoradiotherapy and esophagectomy for esophageal cancer

Faisal A. Siddiqui, Katelyn M. Atkins, Brian S. Diggs, Charles R. Thomas Jr, John G. Hunter, James P. Dolan

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Jessica Cheng, Malcolm H. Squires III, John L. Mikell, Sarah B. Fisher, Charles A. Staley III, David A. Kooby, Bassel F. El-Rayes, Walter J. Curran Jr, William A. Hall, Lauren E. Colbert, Joseph W. Shelton, Shishir K. Maithel, Jerome Landry, David S. Yu

Impact of intensity modulated radiation therapy on survival in anal cancer

Jaymin Jhaveri, Lael Rayfield, Yuan Liu, Mudit Chowdhary, Sibo Tian, Richard J. Cassidy, Theresa Gillespie, Pretesh R. Patel, Jerome C. Landry, Kirtesh R. Patel

Immune profiling of microsatellite instability-high and polymerase ε (POLE)-mutated metastatic colorectal tumors identifies predictors of response to anti-PD-1 therapy

Chongkai Wang, Jun Gong, Travis Y. Tu, Peter P. Lee, Marwan Fakih

Palliative care and end-of-life health care utilization in elderly patients with pancreatic cancer

Nizar Bhulani, Arjun Gupta, Ang Gao, Jenny Li, Chad Guenther, Chul Ahn, Elizabeth Paulk, Stephanie Houck, Muhammad S. Beg

Distinctive features of gastrointestinal stromal tumors arising from the colon and rectum

Rebecca Zhu, Fangfang Liu, Gabriella Grisotti, Javier Pérez-Irizarry, Charles H. Cha, Caroline H. Johnson, Daniel J. Boffa, Dale Han, Kimberly L. Johung, Yawei Zhang, Sajid A. Khan

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Alcoholic liver disease- Hepatocellular carcinoma transformation

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Pancreatic adenocarcinoma pathology: changing “landscape”

Lodewijk A. A. Brosens, Wenzel M. Hackeng, G. Johan Offerhaus, Ralph H. Hruban, Laura D. Wood

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Below are the latest Journal of Gastrointestinal Oncology articles published online ahead of print publication.

Brief Reports

Patterns of KRAS, NRAS, and BRAF mutations in colorectal cancer in Chile: a 3-year real-world evidence [2019–2021]—a brief report

Fernando Sigler Chávez, Pelegrino Romano De la Torre, Wladimir Flores, Nicolas Cueto, Marcelo Garrido Villanueva, Javiera Veas-Torres, Daniela I. Miranda, Felipe Salinas Barriga, María E. Avendaño, Cristopher San Martin Abello, Andrea C. Sabioncello H., Mauricio A. Sáez, Marialvis Nava Brito, Tania Manriquez Flores, Henry Barrios, Juan A. Godoy, Marcelo Garrido

Published online: 30 April 2026

Original Article

Identification and preliminary examination of prognostic genes linked to calcium metabolism in colorectal cancer

Chao Liang, Xiao-jiang Yi, Jia-li Liu, Hai-peng Huang, Tian-ming Jiang, Jing-fang Diao

Published online: 30 April 2026

Original Article

Mining and experimental validation of machine learning-based immune-related diagnostic biomarkers for hepatocellular carcinoma

Wei Li, Hang Jiang, Jian Duan, Jinlan He, Liping Zhao, Guoping Zhong, Chenghu Fan

Published online: 30 April 2026

Original Article

Single-cell transcriptomics reveals the prognostic and immune infiltration significance of FOLFOX-bevacizumab treatment and lysine crotonylation characteristics in colon cancer

Shiyang Zhan, Shurong Huang, Yangqiang Wang, Wei Zheng, Zongda Cai, Jinping Chen

Published online: 29 April 2026

Original Article

The role of number-of-excitations (NEX) for the usability of freebreathing acquired diffusion-derived ‘vessel density’ (DDVD) and slow diffusion coefficient (SDC) maps in separating liver cysts, hemangiomas, and solid masses with a focus on small lesions

Ming-Hua Sun, Cai-Ying Li, Xin-Yue Xu, Chuan-Jun Xu, Peng-Fei Rong, Yì Xiáng J. Wáng

Published online: 28 April 2026

Original Article

Tumor growth suppression of ivermectin in gastric cancer cell lines and primary gastric cancer organoids

Sunwoong Lee, Deuk Kju Jung, Dohyang Kim, Hee Jeong Lim, Su Youn Nam

Published online: 26 April 2026

Original Article

Global burden landscape (1990–2021) of gallbladder and biliary tract cancer attributable to high body mass index in older adults and a projection to 2050

Pingping Chen, Wenhao Qin, Bing Hu

Published online: 26 April 2026

Original Article

Identification and functional validation of SPON2 as a novel biomarker for the diagnosis and prognosis in hepatocellular carcinoma

Wanrong He, Zehua He, Qingfeng Chen, Wei Lan, Guo Zhang

Published online: 24 April 2026

Original Article

A prognostic nomogram based on log odds of positive lymph nodes to predict survival in gastric cancer patients with neoadjuvant chemotherapy: a large population-based cohort study and external validation

Jun Yang, Yuheng Jin, Xiangning Chen, Wei Jin, Pengfei Wang, Fanghao Mao, Jun Cheng, Jinji Jin

Published online: 23 April 2026

Journal highlight more

Journal of Gastrointestinal Oncology is an open-access, international peer-reviewed journal indexed by PubMed/PubMed Central, Science Citation Index Expanded (SCIE), with a focus on the diagnosis, prevention and clinical investigations of gastrointestinal cancer, including but not limited to, multimodality therapy, markers, imaging and tumor biology.