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Original Article

Effects of polymer terminal group inside micelle core on paclitaxel loading promoting and burst release suppressing
Haiwei He, Nian Huang, Zhiwen Qiu, Lei He, Jiahao Guo, Mingjuan Xu, Wei Li
Esophageal cancer stem cells reduce hypoxia-induced apoptosis by inhibiting the GRP78-perk-eIF2α-ATF4-CHOP pathway in vitro
Ruijiang Lin, Minjie Ma, Biao Han, Ya Zheng, Yuping Wang, Yongning Zhou
Nestin overexpression reduces the sensitivity of gastric cancer cells to trastuzumab
Yi-Chou Wei, Jiang-Yi Zhu, Jing Wu, Shan Yu, Wei Li, Meng-Xuan Zhu, Tian-Shu Liu, Yue-Hong Cui, Qian Li
Tumor mutation burden in gastro-entero-pancreatic-neuroendocrine neoplasms
Sun Young Jeong, Young Suk Park, Jeeyun Lee, Jaeyeon Jang, Youngkyung Jeon, Ye Ji Jung, Daeho Choi, Joohyun Hong, Seung Tae Kim
CircRHOT1 restricts gastric cancer cell ferroptosis by epigenetically regulating GPX4
Huan Wang, Daniel Adam Breadner, Ke Deng, Jing Niu
Outcomes in octogenarians following elective colorectal cancer surgery
Kaushik Thungathurthi, Matthew Wei, Bushra Othman, Anshini Jain, Peter Girdlestone, Raaj Chandra
SOX9 knockout decreases stemness properties in colorectal cancer cells
Mariana Avendaño-Felix, Maribel Aguilar-Medina, José Geovanni Romero-Quintana, Alfredo Ayala-Ham, Adriana S. Beltran, José F. Olivares-Quintero, César López-Camarillo, Carlos Pérez-Plasencia, Mercedes Bermúdez, Erik Lizárraga-Verdugo, Jorge López-Gutierrez, Guzman Sanchez-Schmitz, Rosalío Ramos-Payán
Red cell distribution width—a potential prognostic indicator for colorectal cancer patients after radical resection in China
Weiwei Zhao, Xuefang Shen, Qing Hua, Liu Yang, Ru Zhou, Changming Zhou, Pingbo Xu
The safety and effects of high- and low-volume polyethylene glycol bowel preparation methods before colonoscopy on bowel cleanliness: a systematic review and meta-analysis
Guangting Ma, Xiaojuan Fang
A bioinformatics analysis of potential cellular communication networks in non-alcoholic steatohepatitis and colorectal adenoma using scRNA-seq and bulk-seq
Jiahao Mo, Chang Liu, Zhuolin Li, Longxiu Fan, Shaohua Wu, Hatim Husain, Cailing Zhong, Beiping Zhang
Anti-ferroptotic PRKAA2 serves as a potential diagnostic and prognostic marker for hepatoblastoma
Yi Xie, Zhongqi Cui, Sijia Fang, Guoqing Zhu, Ni Zhen, Jiabei Zhu, Siwei Mao, Fenyong Sun, Qiuhui Pan, Ji Ma
Real-world treatment patterns and survival outcomes for treated biliary tract cancer patients using administrative databases in Ontario
Soo Jin Seung, Hasnain Saherawala, Iqra Syed, Cal Shephard, Derek L. Clouthier, Eric Chen
Prognostic factors and survival prediction in hepatocellular carcinoma: development and validation of a novel nomogram based on the SEER database
Shanshan Huang, Zheng Zhu, Yejiao Ruan, Fayuan Zhang, Yueting Xu, Lingxiang Jin, Victor Lopez-Lopez, Philippe Merle, Guangrong Lu, Liyi Li
The feasibility and safety of the brachial artery approach in the treatment of hepatic artery infusion chemotherapy: a retrospective study
Jian Xiong, Yanyan Zhou, Kai Tan, Haofeng Liu, Yunbao Cao, Junde Liu, Wenhao Wu, Xilin Du, Zhonghua Luo
Addition of transarterial chemoembolization improves outcome of tyrosine kinase and immune checkpoint inhibitors regime in patients with unresectable hepatocellular carcinoma
Yue Hu, Tao Pan, Xi Cai, Quan-Sheng He, Yu-Bao Zheng, Ming-Sheng Huang, Zai-Bo Jiang, Jun-Wei Chen, Chun Wu

Educational Case Series of the Memorial Sloan Kettering Cancer Center

Metastatic well differentiated serotonin-producing pancreatic neuroendocrine tumor with carcinoid heart disease: a case report
Matthew R. Kudelka, Ghassan K. Abou-Alfa, Eileen M. O’Reilly, Michael B. Foote, Bhawna Sirohi, Rawad Elias, Ali Shamseddine, Viktoriya Paroder, Amgad M. Moussa, Paul Cohen, Karuna Ganesh

Case Report

From KIT-mutated into wild-type: dedifferentiation of gastrointestinal stromal tumor in adolescent patient—a case report
Marta Andrzejewska, Jakub Czarny, Jolanta Skalska-Sadowska, Katarzyna Jończyk-Potoczna, Paweł Kurzawa, Mateusz Wichtowski, Jacek Wachowiak, Katarzyna Derwich

Editorial Commentary on Current Management of Upper Gastrointestinal Malignancies1

Robotic surgery for esophageal cancer: what is the evidence?
Francisco Schlottmann, Fernando A. M. Herbella, Marco G. Patti
Antireflux surgery to prevent the progression from Barrett’s esophagus to esophageal adenocarcinoma: yes or no?
Marco G. Patti, Fernando A. Herbella, Francisco Schlottmann

Review Article on Current Management of Upper Gastrointestinal Malignancies1

Controversies in the surgical management of esophageal adenocarcinoma
Stephanie G. Worrell, Daniela Molena
Neoadjuvant and adjuvant therapy in esophageal cancer
Jennifer A. Weiss, Shikha Jain
Current management of gastric adenocarcinoma: a narrative review
Yehonatan Nevo, Lorenzo Ferri
Surgical approach to achieve R0 resections in primary and metastatic liver tumors: a literature review
Paola A. Vargas, Nakul Dar, Eduardo de Souza Martins Fernandes, Nicolas Goldaracena
A more radical perspective on surgical approach and outcomes in pancreatic cancer—a narrative review
Eduardo de Souza M. Fernandes, Felipe Pedreira T. de Mello, Eduardo Pinho Braga, Gabrielle Oliveira de Souza, Ronaldo Andrade, Leandro Savattone Pimentel, Camila Liberato Girão, Munique Siqueira, José Maria A. Moraes-Junior, Romulo Varella de Oliveira, Nicolas Goldaracena, Orlando Jorge M. Torres

Disclosure

1. The series “Current Management of Upper Gastrointestinal Malignancies” was commissioned by the editorial office, Journal of Gastrointestinal Oncology without any funding or sponsorship. Francisco Schlottmann and Marco G. Patti served as the unpaid Guest Editors for the series.

Original Article

The clinical utility of serum CA 19-9 in the diagnosis, prognosis and management of pancreatic adenocarcinoma: An evidence based appraisal
Umashankar K Ballehaninna, Ronald S Chamberlain
Survival of metastatic gastric cancer: Significance of age, sex and race/ethnicity
Dongyun Yang, Andrew Hendifar, Cosima Lenz, Kayo Togawa, Felicitas Lenz, Georg Lurje, Alexandra Pohl, Thomas Winder, Yan Ning, Susan Groshen, Heinz-Josef Lenz

Review Article

Imaging of pancreatic cancer: An overview
Pavan Tummala, Omer Junaidi, Banke Agarwal
Immunohistochemical features of the gastrointestinal tract tumors
Hannah H. Wong, Peiguo Chu
Techniques of hepatic resection
Robert J. Aragon, Naveenraj L. Solomon
Gastric cancer: Classification, histology and application of molecular pathology
Bing Hu, Nassim El Hajj, Scott Sittler, Nancy Lammert, Robert Barnes, Aurelia Meloni-Ehrig
HDR brachytherapy for anal cancer
Peter Niehoff, Gyoergy Kovács
Colorectal carcinoma: Pathologic aspects
Matthew Fleming, Sreelakshmi Ravula, Sergei F. Tatishchev, Hanlin L. Wang

Original Article

Bax expression is a candidate prognostic and predictive marker of colorectal cancer
Venkat R Katkoori, Catalina Suarez-Cuervo, Chandrakumar Shanmugam, Nirag C Jhala, Tom Callens, Ludwine Messiaen, James Posey III, Harvey L Bumpers, Sreelatha Meleth, William E Grizzle, Upender Manne
Survival of metastatic gastric cancer: Significance of age, sex and race/ethnicity
Dongyun Yang, Andrew Hendifar, Cosima Lenz, Kayo Togawa, Felicitas Lenz, Georg Lurje, Alexandra Pohl, Thomas Winder, Yan Ning, Susan Groshen, Heinz-Josef Lenz
The influence of radiation therapy dose escalation on overall survival in unresectable pancreatic adenocarcinoma
William A. Hall, Lauren E. Colbert, Dana Nickleach, Jeffrey Switchenko, Yuan Liu, Theresa Gillespie, Joseph Lipscomb, Claire Hardy, David A. Kooby, Roshan S. Prabhu, John Kauh, Jerome C. Landry
Overall survival analysis of neoadjuvant chemoradiotherapy and esophagectomy for esophageal cancer
Faisal A. Siddiqui, Katelyn M. Atkins, Brian S. Diggs, Charles R. Thomas Jr, John G. Hunter, James P. Dolan
Radiotherapy patterns of care in gastric adenocarcinoma: a single institution experience
Jessica Cheng, Malcolm H. Squires III, John L. Mikell, Sarah B. Fisher, Charles A. Staley III, David A. Kooby, Bassel F. El-Rayes, Walter J. Curran Jr, William A. Hall, Lauren E. Colbert, Joseph W. Shelton, Shishir K. Maithel, Jerome Landry, David S. Yu
Impact of intensity modulated radiation therapy on survival in anal cancer
Jaymin Jhaveri, Lael Rayfield, Yuan Liu, Mudit Chowdhary, Sibo Tian, Richard J. Cassidy, Theresa Gillespie, Pretesh R. Patel, Jerome C. Landry, Kirtesh R. Patel
Immune profiling of microsatellite instability-high and polymerase ε (POLE)-mutated metastatic colorectal tumors identifies predictors of response to anti-PD-1 therapy
Chongkai Wang, Jun Gong, Travis Y. Tu, Peter P. Lee, Marwan Fakih
Palliative care and end-of-life health care utilization in elderly patients with pancreatic cancer
Nizar Bhulani, Arjun Gupta, Ang Gao, Jenny Li, Chad Guenther, Chul Ahn, Elizabeth Paulk, Stephanie Houck, Muhammad S. Beg
Distinctive features of gastrointestinal stromal tumors arising from the colon and rectum
Rebecca Zhu, Fangfang Liu, Gabriella Grisotti, Javier Pérez-Irizarry, Charles H. Cha, Caroline H. Johnson, Daniel J. Boffa, Dale Han, Kimberly L. Johung, Yawei Zhang, Sajid A. Khan

Review Article

Alcoholic liver disease- Hepatocellular carcinoma transformation
Samuel W French, James Lee, Jim Zhong, Timothy R Morgan, Virgil Buslon, William Lungo, Barbara A French
Pancreatic adenocarcinoma pathology: changing “landscape”
Lodewijk A. A. Brosens, Wenzel M. Hackeng, G. Johan Offerhaus, Ralph H. Hruban, Laura D. Wood
Refining the management of resectable esophagogastric cancer: FLOT4, CRITICS, OE05, MAGIC-B and the promise of molecular classification
Jeremy Chuang, Jun Gong, Samuel J. Klempner, Yanghee Woo, Joseph Chao

Original Articles

Socioeconomic status, p53 abnormalities, and colorectal cancer
Emily Vogtmann, Chandrakumar Shanmugam, Venkat R. Katkoori, John Waterbor, Upender Manne
Nab-paclitaxel monotherapy in refractory pancreatic adenocarcinoma
Parvin F. Peddi, May Cho, Jian Wang, Feng Gao, Andrea Wang-Gillam

Below are the latest Journal of Gastrointestinal Oncology articles published online ahead of print publication.

Original Article
Identification of an optimal mutant allele frequency to detect activating KRAS, NRAS, and BRAF mutations in a commercial cell-free DNA next-generation sequencing assay in colorectal and pancreatic adenocarcinomas
Bennett A. Caughey, Kumiko Umemoto, Michelle F. Green, Masafumi Ikeda, Melissa E. Lowe, Makoto Ueno, Donna Niedzwiecki, Hiroya Taniguchi, Daniel J. Walden, Yoshito Komatsu, Rachel D’Anna, Taito Esaki, Tadamichi Denda, Michael B. Datto, Hideaki Bando, Tanios Bekaii-Saab, Takayuki Yoshino, John H. Strickler, Yoshiaki Nakamura
Published online: 19 September 2023