Vol 17, No 3 (June 29, 2026) - Journal of Gastrointestinal Oncology

Original Article

Development of a prognostic prediction model incorporating KDM1B for esophageal squamous cell carcinoma: an integrated transcriptomic and functional analysis

Zhiwei Sun, Ying Yang, Jing Yu, Youwu Shi, Jing Sun, Feng Du, Yanjie Xiao, Songlin Gao, Xiaodong Zhang, Jun Jia

Journal of Gastrointestinal Oncology

2026;

(3)

:131

(29 June 2026)

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Early palliative care decision is associated with reduced end-of-life healthcare utilization in patients with esophageal and gastric cancer

Pauliina Kitti, Nelli-Sofia Nåhls, Sofia Koivusalo, Riikka-Leena Leskelä, Anu Anttonen, Tiina Saarto, Outi Akrén, Timo Carpén

Journal of Gastrointestinal Oncology

2026;

(3)

:132

(29 June 2026)

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Machine learning-based gastric cancer risk prediction in an asymptomatic screening population: a retrospective cohort study

Ji Hyun Song, San Wang, Young Sun Kim, Sun Young Yang, Hae Yeon Kang, Marharyta Kurban, Sanghee Lim, Jeong Yoon Yim

Journal of Gastrointestinal Oncology

2026;

(3)

:133

(29 June 2026)

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Overexpression of TAZ is associated with downregulation of E-cadherin and indicates poor prognosis in gastric cancer: a clinicopathological study

Xijun Luo, Yisi Tu, Danni Wu, Xiuqin Cai, Wenfeng Li, Shibin Yang

Journal of Gastrointestinal Oncology

2026;

(3)

:134

(29 June 2026)

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Evaluating the prognostic value of cuproptosis-related genes and characterizing PDE3B’s role in gastric cancer: integrative bioinformatics analysis and experimental validation

Linhui Chen, Zi Wang, Yanjun Guo, Chenyang Li, Guoxin Zhang

Journal of Gastrointestinal Oncology

2026;

(3)

:135

(29 June 2026)

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p62/SQSTM1-TRAF6/RIP1 complexes activate NF-κB-mediated PD-L1 expression and promote T-cell apoptosis in MKN45 gastric cancer cells

Shiyang Li, Lingling Guo, Xuan Yang, Minwei Yang, Xiaoqian Li, Tao Ye, Min Jiang, Jian Ma

Journal of Gastrointestinal Oncology

2026;

(3)

:136

(29 June 2026)

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Histopathologic, molecular, and clinical associations of fusion-positive gastrointestinal carcinomas

Bennett A. Caughey, Sean T. Bannon, Chloe Simms, Haley Barnes, Leontios Pappas, Valentina Nardi, Dora Dias-Santagata, A. John Iafrate, Ryan B. Corcoran, Charlotte I. Wang

Journal of Gastrointestinal Oncology

2026;

(3)

:137

(29 June 2026)

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Comparison of endoscopic submucosal dissection and surgery for early signet-ring cell carcinoma of the stomach: a multicenter study

Xinying Yu, Jian Chen, Xiao Liu

Journal of Gastrointestinal Oncology

2026;

(3)

:138

(29 June 2026)

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Metabolic profile alterations as early indicators of gastrointestinal stromal tumors (GISTs) recurrence and imatinib resistance

Allen Lin Luo, Allen Seylani, Yohannes Haile, Assal Sadighian, Sadaf Sadighian, Mark Agulnik

Journal of Gastrointestinal Oncology

2026;

(3)

:139

(29 June 2026)

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A nomogram for predicting progression-free survival in stage III–IV gastric cancer based on post-treatment cholinesterase and C-reactive protein

Dan Hu, Yumin Wang, Yongjie Zhang

Journal of Gastrointestinal Oncology

2026;

(3)

:140

(29 June 2026)

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Efficacy and safety of modified FLOT chemotherapy in gastric or gastroesophageal junction adenocarcinoma: a retrospective cohort study

Cody Eslinger, Oudai Sahwan, Fares Jamal, Douglas Dias e Silva, Skye Buckner-Petty, Jennah Bauernfeind, Daniel Ahn, Mitesh J. Borad, Christina Wu, Mojun Zhu, Nabil Wasif, Jason Starr, Umair Majeed, Tanios Bekaii-Saab, Pedro Luiz Serrano Uson, Mohamad Bassam Sonbol

Journal of Gastrointestinal Oncology

2026;

(3)

:141

(29 June 2026)

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Excess late mortality among long-term gastric cancer survivors following gastrectomy: a population-based cohort study

Yi Fu, Jian Li

Journal of Gastrointestinal Oncology

2026;

(3)

:142

(29 June 2026)

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Tumor growth suppression of ivermectin in gastric cancer cell lines and primary gastric cancer organoids

Sunwoong Lee, Deuk Kju Jung, Dohyang Kim, Hee Jeong Lim, Su Youn Nam

Journal of Gastrointestinal Oncology

2026;

(3)

:143

(29 June 2026)

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A prognostic nomogram based on log odds of positive lymph nodes to predict survival in gastric cancer patients with neoadjuvant chemotherapy: a large population-based cohort study and external validation

Jun Yang, Yuheng Jin, Xiangning Chen, Wei Jin, Pengfei Wang, Fanghao Mao, Jun Cheng, Jinji Jin

Journal of Gastrointestinal Oncology

2026;

(3)

:144

(29 June 2026)

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Rising prevalence of venous thromboembolism in gastrointestinal cancers: a nationwide analysis of 205 million hospitalizations, 2016–2022

Kuldeepsinh Pradipkumar Atodaria, Arpeet Patel, Niharika Kottapalli, Pratap Tetali, Sabah Iqbal, Samyak Dhruv, Tarun Parvataneni, Steven J. Cohen, Ammar Ashfaq

Journal of Gastrointestinal Oncology

2026;

(3)

:145

(29 June 2026)

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Comparison of preoperative urinary Titin levels and serum Titin levels in patients with gastrointestinal malignancy

Mitsugi Shimoda, Kihiro Izumi, Masahiro Shiihara, Mitsuru Watanabe, Ryoichi Miyamoto, Jiro Shimazaki, Shuji Suzuki

Journal of Gastrointestinal Oncology

2026;

(3)

:146

(29 June 2026)

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Independent prognostic value of tumor deposits in stage III colorectal cancer: a large-scale systematic review and meta-analysis

Jiankun Liao, Haiquan Qin, Linghou Meng, Wentao Wang, Haotang Wei, Xianwei Mo

Journal of Gastrointestinal Oncology

2026;

(3)

:147

(29 June 2026)

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SOX18 knockdown inhibits colorectal cancer metastasis and angiogenesis through regulation of SAPK/JNK and PI3K/AKT/mTOR signaling pathways

Xiao Deng, Ping Shuai, Suyun Liu, Xiansen Zhu, Zuohua Miao

Journal of Gastrointestinal Oncology

2026;

(3)

:148

(29 June 2026)

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Nursing-led enhanced recovery bundled care in colorectal cancer surgery: a systematic review and meta-analysis

Wei Pan, Yan-Ling Yang, Na Che, Ying Li, Qian Ma

Journal of Gastrointestinal Oncology

2026;

(3)

:149

(29 June 2026)

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Association of the global inflammatory-nutritional index (GINI) with time to next treatment and overall survival in patients with metastatic colorectal cancer receiving third-line therapy: a real-world retrospective study

Meilu Du, Song Gao, Qi Shi, Susu Han, Wang Yao, Yufei Tang, Xiaoling Yin, Tingting Zhu

Journal of Gastrointestinal Oncology

2026;

(3)

:150

(29 June 2026)

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Paeoniflorin inhibits colorectal cancer stem cell properties via regulating LINC01711/KMT2D/KLF7 axis

Wei Wang, Mei Li, Fan Hu, Renjing Lin, Chongsi Xu, Biao Xie

Journal of Gastrointestinal Oncology

2026;

(3)

:151

(29 June 2026)

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Development of a multivariable prediction model for tumor response and treatment tolerance based on body composition dynamics in rectal cancer undergoing neoadjuvant chemoradiotherapy

Soohyeon Lee, Dong Hyun Kang, Tae Sung Ahn

Journal of Gastrointestinal Oncology

2026;

(3)

:152

(29 June 2026)

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Younger age at colorectal cancer diagnosis in hereditary gastrointestinal cancer predisposition syndromes and Lynch syndrome: a nationwide analysis

Mohamed H. Eldesouki, Ahmed Ibrahim, Bryson W. Katona, Carol Burke, Aasma Shaukat

Journal of Gastrointestinal Oncology

2026;

(3)

:153

(29 June 2026)

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Integrating network pharmacology, molecular docking, and experimental verification to investigate the mechanism of baicalein in colorectal cancer

Jiahe Wang, Kunyu Han, Bingkun Chen, Yupei Guo, Jinyan Zhao, Xiaoqin Zhu, Jiumao Lin, Yong Chen

Journal of Gastrointestinal Oncology

2026;

(3)

:154

(29 June 2026)

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Deep learning model based on MRI-derived microvascular network simulation parameters for noninvasive assessment of lymphovascular invasion in rectal cancer patients

Yue Di, Xiaofeng Jin, Lei Han, Qin Lu, Tingting Han

Journal of Gastrointestinal Oncology

2026;

(3)

:155

(29 June 2026)

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Identification of telomere-related genes in the progression of colon adenocarcinoma: a bioinformatics analysis

Zhiyong Wang, Shuomin Zhang, Yi Dong, Zhikai Li, Zizhan Li, Zhigang Luan, Sen Wang, Jipan Liu, Yong Li

Journal of Gastrointestinal Oncology

2026;

(3)

:156

(29 June 2026)

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Colorectal cancer survival in patients without curative measures: a retrospective cohort study

Aman Saini, Ademola Adeyeye, Hao Gao, Molly Steele, Alisha Jafri, Pranay Ruparelia, Bhavya Manchukonda, Amyn Haji

Journal of Gastrointestinal Oncology

2026;

(3)

:157

(29 June 2026)

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Association between preoperative aspartate aminotransferase-to-platelet ratio index and prognosis in colorectal liver metastases: a systematic review and meta-analysis

Huiwen Li, Yuanyuan Yin, Zongliang Yang, Ning Ding, Yongheng He

Journal of Gastrointestinal Oncology

2026;

(3)

:158

(29 June 2026)

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Transanal drainage tube versus diverting stoma for reducing anastomotic leakage after rectal cancer surgery: a systematic review and meta-analysis

Xiaobin Zhang, Zhao Chen, Zongyu Liang

Journal of Gastrointestinal Oncology

2026;

(3)

:159

(29 June 2026)

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Identification and preliminary examination of prognostic genes linked to calcium metabolism in colorectal cancer

Chao Liang, Xiao-Jiang Yi, Jia-Li Liu, Hai-Peng Huang, Tian-Ming Jiang, Jing-Fang Diao

Journal of Gastrointestinal Oncology

2026;

(3)

:160

(29 June 2026)

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Clinicopathological and molecular profiling of sporadic synchronous multiple primary colorectal cancers: focus on microsatellite instability status

Kai Lv, Hui Yang, Xiangpeng Xi, Yulin Liu, Yongbo Zhang, Jingbo Chen

Journal of Gastrointestinal Oncology

2026;

(3)

:161

(29 June 2026)

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Single-cell transcriptomics reveals the prognostic and immune infiltration significance of FOLFOX-bevacizumab treatment and lysine crotonylation characteristics in colon cancer

Shiyang Zhan, Shurong Huang, Yangqiang Wang, Wei Zheng, Zongda Cai, Jinping Chen

Journal of Gastrointestinal Oncology

2026;

(3)

:162

(29 June 2026)

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Prognostic and therapeutic significance of microscopic tumor focus in combined hepatocellular-cholangiocarcinoma: a multicenter pathological study

Han Wang, Chun-Yan Xia, Xia Sheng, Yun Zhao, Hong-Zhen Chen, Wen-Ming Cong, Miao-Xia He, Hui Dong

Journal of Gastrointestinal Oncology

2026;

(3)

:163

(29 June 2026)

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Sequential surgery following conversion therapy based on combination of immune checkpoint inhibitors and antiangiogenic targeted drugs as a potential approach for advanced hepatocellular carcinoma with portal vein tumor thrombus: a prospective study

Shang Gao, Yanqin Hu, Yinbiao Cao, Weizheng Liu, Hongxiang Jiang, Tong Jiang, Haowen Tang, Shichun Lu

Journal of Gastrointestinal Oncology

2026;

(3)

:164

(29 June 2026)

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A retrospective study on the outcomes of yttrium-90 radiation segmentectomy with resin microspheres compared to microwave ablation for early primary hepatocellular carcinoma

Omar Abdalla, Trey Mcgonigle, Patrick Doyle, Nathaniel Kelm, Tag Alsir Osama, Jared Grice, Shi Huang, Daniel B. Brown, Meaghan Dendy Case

Journal of Gastrointestinal Oncology

2026;

(3)

:165

(29 June 2026)

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The impact of adjuvant chemotherapy on overall survival and cancer-specific survival in patients with extrahepatic cholangiocarcinoma across different age groups: a population-based study

Tingyu Liu, Chang Liu, Hefei Ren, Lin Zhou

Journal of Gastrointestinal Oncology

2026;

(3)

:166

(29 June 2026)

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Mining and experimental validation of machine learning-based immune-related diagnostic biomarkers for hepatocellular carcinoma

Wei Li, Hang Jiang, Jian Duan, Jinlan He, Liping Zhao, Guoping Zhong, Chenghu Fan

Journal of Gastrointestinal Oncology

2026;

(3)

:167

(29 June 2026)

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The role of number-of-excitations (NEX) for the usability of free-breathing acquired diffusion-derived ‘vessel density’ (DDVD) and slow diffusion coefficient (SDC) maps in separating liver cysts, hemangiomas, and solid masses with a focus on small lesions

Ming-Hua Sun, Cai-Ying Li, Xin-Yue Xu, Chuan-Jun Xu, Peng-Fei Rong, Yì Xiáng J. Wáng

Journal of Gastrointestinal Oncology

2026;

(3)

:168

(29 June 2026)

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Identification and functional validation of SPON2 as a novel biomarker for the diagnosis and prognosis in hepatocellular carcinoma

Wanrong He, Zehua He, Qingfeng Chen, Wei Lan, Guo Zhang

Journal of Gastrointestinal Oncology

2026;

(3)

:169

(29 June 2026)

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A nomogram‑based diagnostic prediction model for differentiating mucinous cystic neoplasms from simple hepatic cysts in patients with hepatic cystic lesions

Diao Kong, Yueqing Xu, Wei Peng

Journal of Gastrointestinal Oncology

2026;

(3)

:170

(29 June 2026)

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Global burden landscape (1990–2021) of gallbladder and biliary tract cancer attributable to high body mass index in older adults and a projection to 2050

Pingping Chen, Wenhao Qin, Bing Hu

Journal of Gastrointestinal Oncology

2026;

(3)

:171

(29 June 2026)

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Real-world feasibility and safety of neoadjuvant FOLFIRINOX in pancreatic ductal adenocarcinoma: a retrospective single-center study

Soetkin D’Haens, Antoon Billiet, Halit Topal, Baki Topal, Filip Van Herpe, Jeroen Dekervel

Journal of Gastrointestinal Oncology

2026;

(3)

:172

(29 June 2026)

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A single-cell and machine learning framework identifies CAFs-associated signatures linking stromal heterogeneity to immune regulation in pancreatic cancer

Faliang Xing, Jia Sun, Chun Li, Xin Wu, Bo Zhang, Binglu Li

Journal of Gastrointestinal Oncology

2026;

(3)

:173

(29 June 2026)

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Prognostic value of lactate dehydrogenase-to-albumin ratio in metastatic/recurrent pancreatic cancer treated with first-line gemcitabine plus nab-paclitaxel: a single-center retrospective cohort study

Yoshiya Yamauchi, Atsushi Sofuni, Yuichi Nagakawa, Takao Itoi

A case report of diffuse large B-cell lymphoma and gastric signet ring cell adenocarcinoma in the same anatomic site: a clinical and management conundrum

Steve Oguguo Nwokeocha, Jeyavishnupriya Gopalakrishnan, Dikshya Khatiwada, Ashlesha Chaudhary, Rajat Soni, Pavel Bleik, Anush V. Patel

Journal of Gastrointestinal Oncology

2026;

(3)

:178

(29 June 2026)

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Solid pseudopapillary neoplasm of the pancreas with postoperative multiple liver metastases in an older woman: a case report

Yishan Lu, Nana Huang, Ruzhu Wang, Yuting Zhang, Haitao Duan, Ping Gao

Journal of Gastrointestinal Oncology

2026;

(3)

:179

(29 June 2026)

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Brief Report

Patterns of KRAS, NRAS, and BRAF mutations in colorectal cancer in Chile: a 3-year real-world evidence [2019–2021]—a brief report

Fernando Sigler Chávez, Pelegrino Romano De la Torre, Wladimir Flores, Nicolas Cueto, Marcelo Garrido Villanueva, Javiera Veas-Torres, Daniela I. Miranda, Felipe Salinas Barriga, María E. Avendaño, Cristopher San Martin Abello, Andrea C. Sabioncello H., Mauricio A. Sáez, Marialvis Nava Brito, Tania Manriquez Flores, Henry Barrios, Juan A. Godoy, Marcelo Garrido