Vol 16, No 3 (June 30, 2025): Journal of Gastrointestinal Oncology

Original Article

Efficacy and safety of concurrent radiotherapy and chemotherapy for locally advanced esophageal squamous cell carcinoma: a randomized controlled trial
Jialiang Zhou, Erwen Bao, Gang Wu, Qiang Fan, Yutian Zhao, Yunxia Zhang, Wei Wu, Zhenwu Wang, Fuzheng Zhang, Kuaile Zhao
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:791-801
.
 (30 June 2025) 
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Clinical and endoscopic characteristics of colorectal sessile serrated lesion with dysplasia: a single-center cross-sectional comparative study
Yanping Wu, Yunrong Wang, Bei Zhao, Yifan Li, Weiwei Wang, Wenqi Sun, Longying Xiong, Dan Ge, Jiale Xu, Xiaotan Dou, Xiaoping Zou, Wen Li, Lei Wang, Min Chen
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:802-810
.
 (30 June 2025) 
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Genes associated with calcium signaling have promising diagnostic potential for gastric cancer
Chao Shen, Yichao Yan, Bin Liang, Ji Shi, Yan Wu, Ning Ning, Lin Chen, Ankit Madan, Wei Li
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:811-822
.
 (30 June 2025) 
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CDK12 inhibition enhances oxaliplatin efficacy in gastric cancer by suppressing the MAPK signaling pathway
Dayin Huang, Zhizhong Xiong, Bin Zhong, Xianwen Li, Saddam Ahmed Mohamed, Jiachen Sun, Haoyang Xu, Jianping Guo, Zijian Deng, Xianzhe Li, Khaldoun Almhanna, Yonghe Chen, Lei Lian
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:823-839
.
 (30 June 2025) 
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TRIP6/c-Fos regulating GPX4 modulates gastric cancer growth by inhibiting ferroptosis
Yang Huang, Wentao Zhang, Jilong Shen, Yongxiang Li
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:840-852
.
 (30 June 2025) 
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Toosendanin induces ferroptosis in gastrointestinal stromal tumor cells through the regulation of the NCOA4 ferritinophagy pathway: implications for tumor proliferation, migration, and invasion
Qiao Feng, Yuxi Li, Lincan Zhong, Huwei Nie, Wensheng Yang, Guangyu Chen, Lin Zhang
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:853-864
.
 (30 June 2025) 
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Predictive value of preoperative subcutaneous and intramuscular adipose tissue for the occurrence of postoperative liver metastasis in gastric cancer patients undergoing radical gastrectomy
Di Dai, Zhengyuan Bao, Yinsu Zhu, Meiqin Wang
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:865-874
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 (30 June 2025) 
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Development and validation of a preoperative CT-based body composition nomogram for predicting recurrence-free survival after radical surgery in patients with gastric cancer
Anyi Song, Zhaoheng Huang, Jiahuan Xu, Jinghao Chen, Haipeng Gong, Chunyan Yang, Zhengqi Zhu
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:875-889
.
 (30 June 2025) 
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Impact of cancer-directed surgery for gastric cancer patients with lung metastasis: a prognosis analysis
Zhongyu Tan, Xiyao Du, Mo Zeng, Yingli Huang, Yunlong Cai, Shanshan Huang
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:890-898
.
 (30 June 2025) 
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D-dimer predicts the response of patients with gastric cancer to first-line immunotherapy combined with chemotherapy
Longyu Xu, Yang Li, Kai Wang, Chaomin Liu, Rong Liu, Wenjing Zhang
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:899-908
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 (30 June 2025) 
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Treatment discontinuation associated with perioperative toxicity of FLOT versus XELOX chemotherapy in patients with resectable gastric cancer: prospective randomized trial (PECORINO)
Oleksii Dobrzhanskyi, Vjacheslav Kopetskyi, Eric A. Ross, Jonathan Chernoff, Yevhenii Shudrak, Andrii Kolesnyk, Mykyta Pepenin, Andrii Horodetskyi, Nelja Melnitchouk, Yurii Kondratskyi
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:909-921
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 (30 June 2025) 
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Development and validation of a LASSO-based nomogram for predicting anastomotic leakage in elderly patients after laparoscopic gastrectomy
Na Yang, Ying Deng
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:922-936
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 (30 June 2025) 
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Automated machine learning predicts liver metastases in patients with early-onset gastroenteropancreatic neuroendocrine tumors
Fuli Gao, Jian Chen, Xiaodan Xu
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:937-949
.
 (30 June 2025) 
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A prognostic nomogram utilized lymph node ratio for signet ring cell gastric cancer patients post-surgery
Chao Peng, Ting Li
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:950-964
.
 (30 June 2025) 
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The diagnostic efficiency of tissue factor pathway inhibitor 2 methylation in the detection of colorectal cancer: a systematic review and meta-analysis
Xiao-Ling Wang, Shuo Qin, Li Liu, Yu-Qi Jia, Ying Wang, Yu-Jie Zhou, Bruno Ramos-Molina, Manuel Valladares-Ayerbes, Moritz Eidens, Zhi-Zhen Liu
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:965-977
.
 (30 June 2025) 
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A real-world study of oxaliplatin-induced hypersensitivity in colorectal cancer treatment based on the pharmacovigilance system in China: a cohort study
Jing Xue, Chengcui Huang, Chunmei Dai, Jingwen Xie, Mateusz Jagielski, Emmanuel Gabriel, Xiaoyan Li
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:978-985
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 (30 June 2025) 
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Comprehensive analysis of m6A-related lncRNAs as prognosis factors in the immune microenvironment of colorectal cancer
Tian-Hao Lan, Wei Li, Fei Xu, Fu-Lei Meng, Xing Zhang, Jian-Wei Ma, Ning Yang, Qi-Wei Zhao, Zeng-Ren Zhao
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:986-1000
.
 (30 June 2025) 
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The significance of lymph node metastasis in pT1-2 colorectal cancer
Bolun Song, Liming Wang, Yinggang Chen, Yasumitsu Hirano
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1001-1012
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 (30 June 2025) 
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Impact of occlusal support on postoperative complications in patients with colorectal cancer resections
Masano Sagawa, Hajime Yokomizo, Sachiyo Okayama, Shunsuke Iwamoto, Ryohei Nishiguchi, Shinichi Asaka, Takebumi Usui, Takeshi Shimakawa, Hisashi Yano, Sayaka Yoshiba, Shunichi Shiozawa
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1013-1024
.
 (30 June 2025) 
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Molecular characterisation of Mozambican patients diagnosed with colorectal adenocarcinoma
Carlos Selemane, Dylan Ferreira, Isabel Veiga, Patrícia Rocha, Luisa Jamisse, Landim Buane, Assucena Guisseve, Carla Carrilho, Mamudo Ismail, Manuel R. Teixeira, Lúcio Lara Santos
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1025-1037
.
 (30 June 2025) 
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Log odds of positive lymph nodes-based staging system for colorectal cancer patients with inadequate lymph nodes harvested: a potential reference for adjuvant chemotherapy
Hongwei Wang, Linlin Wang, Zhong Li, Jiahang Zhang, Guohui Liu
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1038-1049
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 (30 June 2025) 
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Efficacy and safety of transcatheter arterial embolization combined with ablation and regorafenib for unresectable hepatocellular carcinoma patients failing first-line treatment: a real-world study
Wenfeng Gao, Yiqi Xiong, Tingting Mei, Christine Pocha, Xavier Adhoute, Pierleone Lucatelli, Yonghong Zhang
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1050-1059
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 (30 June 2025) 
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The long noncoding RNA RMRP-miR-3135a-SV2A axis promotes the development of hepatocellular carcinoma
Ying Wang, Chao Chen, Haozhe Huang, Lichao Xu, Francisco Tustumi, Jun Liu, Wentao Li
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1060-1077
.
 (30 June 2025) 
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Long-term outcomes of indeterminate focal hepatic observations less than 20 mm followed up with gadoxetic acid-enhanced magnetic resonance imaging (Gd-EOB-DTPA-MRI)
Fei Xing, Yichen Xu, Yue Cao, Lijuan Zhai, Jian Lu, Jifeng Jiang, Qinrong Ma, Wei Xing, Ralf Weiskirchen, Vasileios K. Mavroeidis, Tao Zhang, Songhua Ma
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1078-1091
.
 (30 June 2025) 
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Identification and validation of a ferroptosis-related long non-coding RNA signature as a prognostic biomarker for hepatocellular carcinoma
Tingting Yu, Xiaoxiang Chen, Shuo Li, Morten Ladekarl, Jun Li
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1092-1104
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 (30 June 2025) 
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PANoptosis-associated genes exhibit significant potential in the diagnosis of hepatocellular carcinoma
Yujin Li, Junfeng Li, Yu Chen
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1105-1114
.
 (30 June 2025) 
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The molecular sub-type and the development and validation of a prognosis prediction model based on endocytosis-related genes for hepatocellular carcinoma
Liting Zhang, Dan Zhou, Xiaoqin Gao, Junfeng Li, Xiaodong Xie
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1115-1126
.
 (30 June 2025) 
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Characterization of T cell proliferation-associated hepatocellular carcinoma subtypes, predictive signatures, and candidate targets
Qi Yang, Le Liu, Yawen Zhu, Zhengchao Shen, Yifan Xu, Mengjie Zhang, Xi Chen
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1127-1143
.
 (30 June 2025) 
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Lower diffusion-derived vessel density (DDVD) measure of liver focal nodular hyperplasia than those of hepatocellular carcinoma and liver metastasis allows potential differential diagnosis: quantitative and semi-quantitative analyses of two-center data
Cun-Jing Zheng, Dian-Qi Yao, Cai-Ying Li, Xiao-Hui Duan, Ge Zhang, Zhuo-Heng Yan, Guang-Zi Shi, Xin-Ming Li, Jun Shen, Yì Xiáng J. Wáng
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1144-1156
.
 (30 June 2025) 
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Evaluating the combined diagnostic power of alpha-fetoprotein and protein induced by vitamin K absence or antagonist-II for hepatocellular carcinoma
Shangdi Zhang, Caiyan Gao, Yubin Wang, Linmei Chen, Shan Gao
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1157-1175
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 (30 June 2025) 
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Expression of PDZ domain-containing proteins is correlated with prognosis and immune infiltration in hepatocellular carcinoma
Xiaozhen Song, Yujia Lin, Chi Wu, Miaoxin Zhang, Longjun Yang, Ninghui Zhao, Panpan Lu, Qiang Ding, Qinghai Tan, Mei Liu
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1176-1195
.
 (30 June 2025) 
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Comparison analysis of different doses bevacizumab plus ICIs and interventional therapy in unresectable hepatocellular carcinoma: a real-world study
Miao Li, Tong Li, Yi Chen, Ningling Ge, Biwei Yang, Rongxin Chen, Yinghao Shen, Lan Zhang
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1196-1207
.
 (30 June 2025) 
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A novel miRNA-based model for predicting the 3-year recurrence risk of hepatocellular carcinoma following liver transplantation
Bin Yu, Youming Ding
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1208-1219
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 (30 June 2025) 
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Impact of postoperative chemotherapy on the prognosis of combined hepatocellular-cholangiocarcinoma: a retrospective study based on the SEER database
Yunxi Lu, Lulu Zheng, Huihong Mei
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1220-1232
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 (30 June 2025) 
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Genetically proxied risk and protective factors for pancreatic cancer: a systematic review and meta-analysis of Mendelian randomization studies
Fada Luo, Weicheng Mou, Yong Zeng, Xingwei Ouyang, Richard J. Bold, Somashekar G. Krishna, Atsushi Yamaguchi, Li Zhang
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1233-1247
.
 (30 June 2025) 
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Peripheral blood neutrophil-to-lymphocyte ratio as a prognostic marker and its association with the tumor-immune microenvironment in pancreatic cancer: a retrospective cohort study
Jing Li, Jiayi Wang, Yuxuan Li, Wenna Jiang, Duo Zuo, Xiuse Zhang, Jiawei Xiao, Kentaro Inamura, Elisa Giovannetti, Li Ren
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1248-1257
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 (30 June 2025) 
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Imaging prediction of lymph node metastasis and early recurrence in patients with distal cholangiocarcinoma
Yizhe Wang, Jingjing Yao, Liang Wang, Zhuozhao Zheng, Chen Zhang, Jie Li
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1258-1267
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 (30 June 2025) 
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Real-world effectiveness of anamorelin in patients with unresectable and relapse pancreatic cancer: a prospective observational study
Atsushi Yamaguchi, Hiroki Kamada, Shigeaki Semba, Naohiro Kato, Yuji Teraoka, Takeshi Mizumoto, Yuzuru Tamaru, Tsuyoshi Hatakeyama, Hirotaka Kouno, Yoshiyuki Shibata, Sho Tazuma, Takeshi Sudo, Midori Ishida, Yuki Hotehama, Hidemi Kane, Hisashi Tagashira, Sayo Yoshiyama, Mitsunobu Kubota, Shigeto Yoshida
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1268-1279
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 (30 June 2025) 
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Evolving survival patterns in pancreatic adenocarcinoma: a 23-year retrospective observational analysis
Tiago Cordeiro Felismino, Diego Rodrigues, Angelo Brito, Virgilio Silva, Lais Durant, Heber Ribeiro, Alessandro Diniz, Igor Farias, André Godoy, Silvio Torres, Maria Paula Curado, Felipe Coimbra
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1280-1286
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 (30 June 2025) 
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Comprehensive analysis identifies AMIGO2 as a potential prognosis biomarker of pancreatic adenocarcinoma
Jiawei Cao, Tong Zhou, Jiayu Chen, Dejin Shi, Xueting Liu, Changrui Qian, Guang Wu, Shaofei Yuan, Lan Li
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1287-1304
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 (30 June 2025) 
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Influence of pre-operative sarcopenia on post-operative hepatic steatosis after pancreaticoduodenectomy for pancreatic ductal adenocarcinoma
Louis Caputo, Yasmina Richa, Kaja Balcer, César Beugniez, Mathilde Vermersch, Julien Bourry, Emeline Cailliau, Stephanie Truant, Mehdi El Amrani
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1305-1313
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 (30 June 2025) 
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Case Report: iMDT Corner

Camrelizumab plus sorafenib or apatinib achieved long-term survival in a patient with hepatocellular carcinoma and an Eastern Cooperative Oncology Group performance status of 3: a case report
Xin Wang, Guangbin Ji, Xi Chen, Hongbo Hu, Lianyue Zou, Haruhiko Takeda, Caiyun Zhou
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1314-1320
.
 (30 June 2025) 
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Case Report

Liver transplantation in a patient with metastatic hepatocellular carcinoma after downstaging with single-agent immunotherapy: the first case report
Angelo Pirozzi, Celine Hoyek, Oluseyi Abidoye, Naohiro Okano, Michelle C. Nguyen, Thomas Byrne, Bashar Aqel, David Chascsa, Sadeer Alzubaidi, Lorenza Rimassa, Tanios Bekaii-Saab, Mitesh J. Borad
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1321-1330
.
 (30 June 2025) 
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Multimodal imaging in hepatic epithelioid angiomyolipoma: a case report
Shuyue Yan, Xuedong Wang, Xiangrong Yu
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1331-1338
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 (30 June 2025) 
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Surgical Technique

A modified combined approach in laparoscopic right hemicolectomy for right-sided colon based on surgical trunk orientation: a case of a new surgical technique
Yexing Xu, Jiaxi Tang, Paul C. Kuo, Renli Huang, Zhaowei Zou
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1339-1346
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 (30 June 2025) 
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Editorial

Path towards personalized care of hepatocellular carcinoma: a nomogram for survival prediction
Nicole Tan, Vishal G. Shelat
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1347-1350
.
 (30 June 2025) 
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Editorial Commentary

Targeting metabolism in pancreatic ductal adenocarcinoma: challenges and insights from the AVENGER 500 trial
Elizabeth S. Nakasone, Andrew L. Coveler
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1351-1355
.
 (30 June 2025) 
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Letter to the Editor

Critical analysis of prognostic study in esophageal squamous cell carcinoma
Dong-Mei Liu, Jian Zhang
Journal of Gastrointestinal Oncology  
2025;
16
(3)
:1356-1357
.
 (30 June 2025) 
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