Vol 16, No 2 (April 30, 2025): Journal of Gastrointestinal Oncology

Original Article

Efficacy and safety of camrelizumab in combination with S-1 plus oxaliplatin sequenced by camrelizumab-based maintenance therapy as a first-line treatment for advanced gastric or gastroesophageal junction adenocarcinoma: a retrospective cohort study
Wan-Ren Peng, Fei Zhang, Wen-Wen Ma, Jie Da, Han-Qing Yu, Lu-Lu Fan, Zhen-Ya Jia, Jing Xu, Zi-Cong Gao, Chang-Chun Shao, Guo-Ping Sun
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:342-353
.
 (30 April 2025) 
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Efficacy observation of sequential TAS-102 following regorafenib as a later-line treatment in patients with metastatic colorectal cancer: a cohort study
Chang Xu, Xiangyu Cheng, Changqing Liu, Jing Ren, Vishal G. Shelat, Timothy Price, José María Sayagués, Yi Gai, Guangyu Wang, Yusheng Wang
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:354-366
.
 (30 April 2025) 
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The unique role of cuproptosis in the prognosis and treatment of rectum adenocarcinoma
Jun Ma, Huangwei Lin, Ying Wang, Yaming Zhang, Chaoping Zhou, Daibin Tang, Yoshinori Kagawa, Daorong Hou, Guoqin Jiang
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:367-385
.
 (30 April 2025) 
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Prognostic role of tertiary lymphatic structures and their modulation by adjuvant FOLFOX in stage III colon cancer: a retrospective cohort study
Chuang Zhang, Shao-Ke Wang, Nan Zun Teo, Matthew Yuan-Kun Wei, Hiroki Hashida, Chen-Feng Yu, Yan-Long Liu, Bin-Bin Cui
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:386-403
.
 (30 April 2025) 
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Comprehensive genomic profiling of small bowel adenocarcinoma with liver metastasis
Ruixia Jie, Changchao Xiao, Li Wang, Dejian Gu, Yuange He, Leonardo S. Lino-Silva, Keita Kai, Chuanchuan Li, Fang Peng
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:404-414
.
 (30 April 2025) 
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The highly expressed GOLPH3 in colorectal cancer cells activates smoothened to drive glycolysis and promote cancer cell growth and radiotherapy resistance
Kunli Zhu, Jing Fan, Hongchao Cai, Changchun Zhou, Zhe Gong, Zhenxiang Li, Jinming Yu
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:415-434
.
 (30 April 2025) 
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Validation of multiple deep learning models for colorectal tumor differentiation with endoscopic ultrasound images: a dual-center study
Hang Men, Cong Yan, Xi Peng, Shao-Qin Jin, Yu-Hao Du, Zhong-Shun Tang, Hao Li, Ting Ou-Yang, Shuo Zhang, Li-Shan Ding, Jin Deng, Zhe Xu, Guan-Bin Li, Hong-Yu Luo, Zhou Li, Fang Xie, Shuai Han
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:435-452
.
 (30 April 2025) 
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KCNC3 as a prognostic indicator and a predictive marker for immunotherapy in colorectal cancer
Quanqing Li, Jiaying Lv, Hongxia Duan, Pingping Sun, Bing Lu, Wenyu Shi, Yihong Cai
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:453-469
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 (30 April 2025) 
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Bacillus velezensis inhibits azoxymethane/dextran sulphate sodium induced colitis associated colorectal cancer via the small molecule HeLM
Edward Horwell, Charlotte Freer-Smith, Huynh A. Hong, Philip Bearn, Simon M. Cutting
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:470-484
.
 (30 April 2025) 
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A prognostic nomogram based on desmoplastic reaction/tumor deposit modified lymph node staging in colorectal cancer
Longting Geng, Li Wang, Xiaoming Jiang, Changxian Chen, Yunbin Yuan, Weijun Liu, Weimin Bao
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:485-502
.
 (30 April 2025) 
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circFADS2 inhibits ferroptosis associated with IGF2BP2-dependent SLC7A11 m6A modification in colorectal cancer cells
Liangjun Jiang, Xianzhou Lu, Wei Li
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:503-516
.
 (30 April 2025) 
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D3 lymph node dissection improves perioperative outcomes and overall survival in patients with cT2N0 colorectal cancer
Bolun Song, Liming Wang, Yinggang Chen, Yasumitsu Hirano
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:517-527
.
 (30 April 2025) 
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Relationship between apparent diffusion coefficient values and clinicopathologic features in rectal cancer: a cross-sectional study
Chunyu Zhang, Ting Lu, Hongyu Zhang, Yuting Zhang, Long Yuan, Junlin Zhou
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:528-541
.
 (30 April 2025) 
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Efficacy and safety of dose adjustment for fruquintinib in the third-line treatment of metastatic colorectal cancer: a retrospective study with real-world settings
Qun Zhang, Haiqing Niu, Ke Cheng, Xiaoping Qian
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:542-548
.
 (30 April 2025) 
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Prognostic nomogram for T3–T4 primary colorectal cancer patients with perineural invasion after surgery: a Surveillance, Epidemiology, and End Results program database analysis
Hui Wu, Xue Liu, Haitao Chen, Qinghua Yao
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:549-567
.
 (30 April 2025) 
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Lacticaseibacillus casei 393 modulates KRAS and APC expression and cytokine levels in colitis-associated colon cancer
Anne Santerre, María del Rosario Huizar-López, Jaime Coronilla Martínez, Pablo Cesar Ortiz-Lazareno, Josefina Casas-Solís
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:568-579
.
 (30 April 2025) 
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Circulating tumor DNA using a plasma-only assay predicts survival in patients with oligometastatic colorectal cancer after definitive therapy
Enrique Sanz-Garcia, Paloma Peinado, Adrián Peláez, Elena Gonzalez Lopez-Aranda, Rafael Álvarez-Gallego, César Muñoz, Carmen Toledano, Luka Mihic, Justo Ortega, Almudena Lazaro, Begoña Martinez Montesino, Cristina Bressel, Alicia Gonzalo, Ovidio Hernando, Mercedes Lopez, Carmen Rubio, Isabel Fabra, Yolanda Quijano, Emilio Vicente, Antonio Cubillo
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:580-590
.
 (30 April 2025) 
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Is radix ligation of the inferior mesenteric artery effective in Japanese-Style D3 radical lymph node dissection for sigmoid colon and rectal cancer surgery?—a single-center retrospective analysis since 2002
Takayuki Tajima, Masaya Mukai, Kyoko Kishima, Lin Fung Chan, Kazutake Okada, Shigeo Higami, Daiki Yokoyama, Syuji Uda, Sayuri Hasegawa, Hiroyasu Makuuchi
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:591-598
.
 (30 April 2025) 
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Inhibition of hepatocellular carcinoma progression by artesunate via modulation of the TLR4/MyD88/NF-κB signaling pathway
Yongchao Wu, Jianhua Wu, Zhigang Li, Zhonglin Wu, Shunzong Li, Guang Yang, Xiaocui Rong, Qi Wang, Yazhou Li, Qingqing Xia, Gaofeng Shi
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:599-614
.
 (30 April 2025) 
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Construction of a survival prediction model for patients with hepatocellular carcinoma (HCC) based on real clinical data: a single-center retrospective study
Ya-Hui Liu, Yun-Wei Yan, Shu-Fan Wei, Wen-Juan Wang, Hong-Ji Zeng, Rui Wang, Qing-Feng Tian
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:615-627
.
 (30 April 2025) 
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Multi-omics analyses develop and validate the optimal prognostic model on overall survival prediction for resectable hepatocellular carcinoma
Ying Han, Ajuan Zeng, Xueying Liang, Yingying Jiang, Fenglin Wang, Lele Song
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:628-649
.
 (30 April 2025) 
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A retrospective database analysis to understand treatment patterns and outcomes of intermediate and advanced hepatocellular carcinoma in Alberta, Canada (A-CAPTAIN study)
Carla P. Amaro, Chloe A. Lim, Philip Q. Ding, Winson Y. Cheung, Iqra Syed, YongJin Kim, Cal Shephard, Sharon Wang, Derek L. Clouthier, Vincent C. Tam
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:650-659
.
 (30 April 2025) 
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Camrelizumab in combination with chemotherapy and targeted therapy improves the prognosis in patients with advanced biliary tract cancer: a single-center retrospective clinical study
Yizhuo Zhang, Xiaolong Liu, Guixing Jiang, Xinyu Dong, Hong Jae Chon, Giovanni Brandi, Daniel Neureiter, Defei Hong
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:660-670
.
 (30 April 2025) 
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Claudin 18 immunohistochemistry in cholangiocarcinoma
Niyati Desai, Huaibin M. Ko, Michael Lee, Ladan Fazlollahi, Ryan H. Moy, Sam S. Yoon, Helen Remotti, Brynn Levy, Andrew T. Turk, Stephen M. Lagana
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:671-678
.
 (30 April 2025) 
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Downregulation of CPT2 promotes proliferation and migration through the TNFα/NF-κB pathway in cholangiocarcinoma
Jun Mao, Genfa Yi, Henghai Yu, Qiaoli Qu, Ying Hu
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:679-698
.
 (30 April 2025) 
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Review Article

Safety and efficacy of pemigatinib in patients with cholangiocarcinoma: a systematic review
Warda Rasool, Yassine Alami Idrissi, Owais Ahmad, Shree Rath, Fatima Saeed, Mohamed Saad Sayed, Bhavya Sharma, Arwa Amer Ibrahim, Ajanta Kumari, Irfan Ullah, Anwaar Saeed
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:699-710
.
 (30 April 2025) 
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The potential of multi- and single-cancer blood-based early detection tests in liver cancer screening
Won Jin Choi, Nima Nabavizadeh
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:711-718
.
 (30 April 2025) 
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Case Report

Humor me with calcium: a case report of humoral hypercalcemia of malignancy secondary to cholangiocarcinoma
Kaiser Kabir, David I. LeRoy, Bhavana Liyanaarachchi, Zainab Shams, Ved Singla
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:719-725
.
 (30 April 2025) 
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Metastatic pancreatic acinar cell carcinoma with BRCA2 gene alternation resected after modified FORFIRINOX therapy: a case report and literature review
Shuhei Sugata, Atsushi Yamaguchi, Hiroki Kamada, Shigeaki Semba, Naohiro Kato, Yuji Teraoka, Takeshi Mizumoto, Yuzuru Tamaru, Tsuyoshi Hatakeyama, Hirotaka Kouno, Yoshiyuki Shibata, Sho Tazuma, Takeshi Sudo, Rie Yamamoto, Kazuya Kuraoka, Shigeto Yoshida, Shiro Oka
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:726-737
.
 (30 April 2025) 
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Autoimmune enteropathy associated with T cell large granular lymphocytic leukemia in a patient with BACH2 mutation: a case report
Juwairiya Arshi, Andrew G Evans, Jane Liesveld, Yansheng Hao
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:738-742
.
 (30 April 2025) 
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Primary gastric squamous cell carcinoma in a young adult with immunotherapy complications: a case report
Yu-Han Chen, Bowon Joung, Dani Ran Castillo, Gagandeep Brar
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:743-749
.
 (30 April 2025) 
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Case Series

Biomarker-driven therapeutic strategies in advanced gastric cancer: a case series of curative responses
Daniel Park, Lu Pu, Mengni Guo, Won Jin Jeon, Esther Chong, Kiwon Park, Yufei Liu, Gagandeep Brar, Chung-Tsen Hsueh, Dani Ran Castillo
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:750-756
.
 (30 April 2025) 
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Systemic chemotherapy in patients with unresectable pseudomyxoma peritonei from low-grade appendiceal mucinous neoplasms: a case series
Mason Vierra, Ryan B. Morgan, Arsha Ostowari, Kiran K. Turaga, Ardaman Shergill, Oliver S. Eng
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:757-765
.
 (30 April 2025) 
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Surgical Technique

Using an indocyanine green fluorescent imaging technique for laparoscopic rectal cancer surgery: a case report
Youqiang Liu, Songjie Li, Zhenya Zhang, Chenhui Li, Pengwei Li, Hongqing Ma, Guiying Wang
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:766-777
.
 (30 April 2025) 
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Four clamp-crush techniques in robotic hepatectomy (with video)
Koji Kikuchi, Hiroyuki Nitta, Akira Umemura, Hirokatsu Katagiri, Shoji Kanno, Daiki Takeda, Taro Ando, Satoshi Amano, Toma Kawashima, Taku Kimura, Hiroaki Shimada, Akihito Jo, Akira Sasaki
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:778-785
.
 (30 April 2025) 
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Editorial

Potential metastatic mechanisms and clinical aspects in patients with non-gastrointestinal tumor metastasis to the upper gastrointestinal tract
Magnus Sundbom
Journal of Gastrointestinal Oncology  
2025;
16
(2)
:786-790
.
 (30 April 2025) 
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