Vol 12, No 5 (October 31, 2021): Journal of Gastrointestinal Oncology

Original Article

Role of surgery following neoadjuvant chemoradiation in patients with lymph node positive locally advanced esophageal adenocarcinoma: a national cancer database analysis
Hirva Mamdani, Thomas Birdas, Shadia I. Jalal
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:1944-1950
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 (31 October 2021) 
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Prognostic impact of lymph node harvest for patients with node-negative esophageal squamous cell carcinoma: a large-scale multicenter study
Qi-Xin Shang, Yu-Shang Yang, Li-Yan Xu, Hong Yang, Yin Li, Yi Li, Zhi-Yong Wu, Jian-Hua Fu, Xiao-Dong Yao, Xiu-E Xu, Jian-Yi Wu, Long-Qi Chen
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:1951-1962
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 (31 October 2021) 
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Prognostic models for stage I–III esophageal cancer: a comparison between existing calculators
Riccardo Lemini, Tamara Díaz Vico, Denslow A. Trumbull, Kristopher Attwood, Aaron C. Spaulding, Enrique F. Elli, Dorin T. Colibaseanu, Moshim Kukar, Emmanuel Gabriel
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:1963-1972
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 (31 October 2021) 
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The comparisons of three stapler placement methods for intrathoracic mechanistic circular stapling in Ivor Lewis minimally invasive esophagectomy
Bo Zhang, Zixiang Wu, Qi Wang, Saibo Pan, Lian Wang, Gang Shen, Huiping Chai, Ming Wu
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:1973-1984
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 (31 October 2021) 
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Trichostatin A enhances radiosensitivity and radiation-induced DNA damage of esophageal cancer cells
Shaobo Wang, Min Song, Bo Zhang
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:1985-1995
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 (31 October 2021) 
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The expression and clinical value of tumor infiltrating dendritic cells in tumor tissues of patients with esophageal cancer
Yanzhi Pei, Yanzhi Zhu, Xiaolin Wang, Lin Xu
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:1996-2003
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 (31 October 2021) 
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Preliminary evaluation of postoperative radiotherapy with small T-shaped field in thoracic esophageal squamous cell carcinoma
Qi Zhao, Jiaxing Zhu, Yandong Liu, Songbing Qin, Juying Zhou
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2004-2012
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 (31 October 2021) 
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Comparison of efficacy and safety between pembrolizumab combined with chemotherapy and simple chemotherapy in neoadjuvant therapy for esophageal squamous cell carcinoma
Bingjiang Huang, Haiyan Shi, Xiaohua Gong, Jing Yu, Caixia Xiao, Bin Zhou, Zibin Liang, Xiaojian Li
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2013-2021
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 (31 October 2021) 
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Combination of the ratio between metastatic and harvested lymph nodes and negative lymph node count as a prognostic indicator in advanced gastric cancer: a retrospective cohort study
Jianlong Jiang, Jingyao Chen, Hao Zhang, Xionghui Rao, Tengfei Hao, Mingzhe Li, Changhua Zhang, Wenhui Wu, Yulong He
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2022-2034
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 (31 October 2021) 
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Apatinib plus S-1 for previously treated, advanced gastric or gastro-oesophageal junction adenocarcinoma: a phase 2, single-arm, prospective study
Chao Jing, Zhigang Bai, Jun Zhang, Hongpeng Jiang, Xiaobao Yang, Shu Yan, Jie Yin, Jun Cai, Zhongtao Zhang, Wei Deng
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2035-2044
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 (31 October 2021) 
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Deploying an artificial intelligence-based online search tool to increase patients’ access to and understanding of solid tumor gastrointestinal clinical trials
Emily Rose Jordan, Luca Jahreiss, Pashtoon Murtaza Kasi
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2045-2051
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 (31 October 2021) 
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Clinical application of nano-carbon to improve the accuracy of lymph node staging in patients with advanced gastric cancer receiving neoadjuvant chemotherapy: a prospective randomized controlled trial
Peigang Yang, Yuan Tian, Bibo Tan, Pingan Ding, Honghai Guo, Yang Liu, Zhidong Zhang, Yong Li, Qun Zhao
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2052-2060
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 (31 October 2021) 
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MiR-873-5p targets THUMPD1 to inhibit gastric cancer cell behavior and chemoresistance
Qinggui Chen, Li Lin, Boliang Xiong, Wensheng Yang, Junli Huang, Huibo Shi, Zhenfa Wang
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2061-2072
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 (31 October 2021) 
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Correlation between L3 skeletal muscle index and prognosis of patients with stage IV gastric cancer
Zheng Kang, Lingling Cheng, Kang Li, You Shuai, Ke Xue, Yuejiao Zhong, Lingxiang Chen
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2073-2081
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 (31 October 2021) 
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Prediction and prognostic significance of ALOX12B and PACSIN1 expression in gastric cancer by genome-wide RNA expression and methylation analysis
Zhiping Liu, Lei Li, Xindi Li, Mingtao Hua, Huaqing Sun, Shengui Zhang
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2082-2092
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 (31 October 2021) 
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Long non-coding RNA HAGLROS regulates the proliferation, migration, and apoptosis of esophageal cancer cells via the HAGLROS-miR-206-NOTCH3 axis
Ling Gai, Yeqing Huang, Lingling Zhao, Feng Li, Zhixiang Zhuang
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2093-2108
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 (31 October 2021) 
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Identification of potential core genes in gastric cancer using bioinformatics analysis
Changjiang Shao, Rong Wang, Dandan Kong, Qian Gao, Chunfang Xu
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2109-2122
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 (31 October 2021) 
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Clinical values and potential pathways of miR-183-5p in gastric cancer: a study based on integrational bioinformatics analysis
Yanan Wang, Jinku Zhang, Mingkai Liu, Shun Zhang, Weina Wang, Shujie Cheng
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2123-2131
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 (31 October 2021) 
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Comprehensive bioinformatics analyses identified Homeobox B9 as a potential prognostic biomarker and therapeutic target for gastric cancer
Xiaofei Li, Shujia Chen, Yinghui Zhu, Jiayue Fei, Liaoyuan Song, Guoyan Sun, Wei Niu, Lianyi Guo, Jiwei Wang
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2132-2149
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 (31 October 2021) 
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Outcome of surgical treatment for bone metastases caused by colorectal cancer
Martina Byttner, Rikard Wedin, Henrik Bauer, Panagiotis Tsagozis
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2150-2156
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 (31 October 2021) 
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Six mutator-derived lncRNA signature of genome instability for predicting the clinical outcome of colon cancer
Shujia Chen, Xiaofei Li, Jiachen Zhang, Li Li, Xueqiu Wang, Yinghui Zhu, Lianyi Guo, Jiwei Wang
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2157-2171
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 (31 October 2021) 
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Establishment and verification of a prognostic tumor microenvironment-based and immune-related gene signature in colon cancer
Tianyu Guo, Zhe Wang, Yefu Liu
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2172-2191
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 (31 October 2021) 
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ATG16L2 overexpression is associated with a good prognosis in colorectal cancer
Jian Tang, Dongyang Wang, Yuguang Shen, Feng Xue
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2192-2202
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 (31 October 2021) 
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Correlation of c-MET expression with clinical characteristics and the prognosis of colorectal cancer
Xiaorong Lai, Qiumei Dong, Fei Xu, Sipei Wu, Dongyang Yang, Chao Liu, Ying Li, Zijun Li, Dong Ma
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2203-2210
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 (31 October 2021) 
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Survival analysis and prognostic factors of palliative radiotherapy in patients with metastatic colorectal cancer: a propensity score analysis
Li Ba, Qingrui Wang, Haihong Wang, Lisheng Zhu, Tao Zhang, Jinghua Ren, Zhenyu Lin
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2211-2222
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 (31 October 2021) 
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TiaochangXiaoliu decoction inhibits azomethane (AOM)/dextran sulfate sodium (DSS)-induced colorectal cancer by regulating immune response
Kefang Chen, Beiping Zhang, Jianjun Li, Aizhen Pan, Linhui Cao, Xiying Zhao, Suiping Huang, Liudan Chen
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2223-2231
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 (31 October 2021) 
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Comprehensive analysis of immune related lncRNAs in the tumor microenvironment of stage II–III colorectal cancer
Zan Zhang, Yixin Wu, Changyuan Yu, Zhengtai Li, Lida Xu
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2232-2243
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 (31 October 2021) 
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TCGA database analysis of the tumor mutation burden and its clinical significance in colon cancer
Junjie Chen, Anwaier Apizi, Lin Wang, Guanting Wu, Zheng Zhu, Huihui Yao, Guoliang Chen, Xinyu Shi, Bo Shi, Qingliang Tai, Chenglong Shen, Guoqiang Zhou, Lingzhi Wu, Songbing He
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2244-2259
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 (31 October 2021) 
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Safety of biliary stent placement followed by definitive chemoradiotherapy in patients with pancreatic cancer with bile duct obstruction
Sara Hayakawa, Kei Ito, Jin Hayakawa, Keiko Nemoto Murofushi, Katsuyuki Karasawa
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2260-2267
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 (31 October 2021) 
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Outcomes of patients with metastatic pancreatic cancer who progress on first restaging imaging
Jane E. Rogers, Jonathan D. Mizrahi, Graciela M. Nogueras Gonzalez, Rishi Surana, Rachna T. Shroff, Robert Wolff, Gauri R. Varadhachary, Milind M. Javle, Michael Overman, Kanwal Raghav, Shubham Pant
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2268-2274
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 (31 October 2021) 
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Intact SMAD-4 is a predictor of increased locoregional recurrence in upfront resected pancreas cancer receiving adjuvant therapy
Hunter C. Gits, Amy H. Tang, William S. Harmsen, William R. Bamlet, Rondell P. Graham, Gloria M. Petersen, Thomas C. Smyrk, Amit Mahipal, Roman O. Kowalchuk, Jonathan B. Ashman, William G. Rule, Dawn Owen, Michelle A. Neben Wittich, Robert R. McWilliams, Thorvardur Halfdanarson, Wen Wee Ma, Terence T. Sio, Sean P. Cleary, Mark J. Truty, Michael G. Haddock, Christopher L. Hallemeier, Kenneth W. Merrell
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2275-2286
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 (31 October 2021) 
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Construction of a competing endogenous RNA network related to the prognosis of cholangiocarcinoma and comprehensive analysis of the immunological correlation
Ning Wang, Yinghui Zhou, Zhifan Zuo, Ruoyu Wang, Jing Li, Tao Han, Bin Yang
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2287-2309
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 (31 October 2021) 
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Prognostic and immune infiltrates for the Chromobox (CBX) protein family in human pancreatic adenocarcinoma
Qian Li, Lei Fu, Daoyuan Wu, Jufeng Wang
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2310-2324
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 (31 October 2021) 
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ACTR3 promotes cell migration and invasion by inducing epithelial mesenchymal transition in pancreatic ductal adenocarcinoma
Hao Hu, Shuo Zhang, Shuming Xiong, Benshun Hu, Youzhao He, Yuanlong Gu
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2325-2333
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 (31 October 2021) 
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Stereotactic body radiation therapy versus radiofrequency ablation for single small hepatocellular carcinoma: a propensity-score matching analysis of their impact on liver function and clinical outcomes
Masayuki Ueno, Hiroyuki Takabatake, Satoshi Itasaka, Takahisa Kayahara, Youichi Morimoto, Hiroshi Yamamoto, Motowo Mizuno
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2334-2344
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 (31 October 2021) 
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Identification and validation of ferroptosis-associated gene-based on immune score as prognosis markers for hepatocellular carcinoma patients
Jukun Wang, Ke Han, Chao Zhang, Xin Chen, Yu Li, Linzhong Zhu, Tao Luo
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2345-2360
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 (31 October 2021) 
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Identification of heterogeneous nuclear ribonucleoprotein as a candidate biomarker for diagnosis and prognosis of hepatocellular carcinoma
Youli Du, Xiaoou Ma, Dongxu Wang, Yuguang Wang, Tianyu Zhang, Lianjie Bai, Yunlong Liu, Shaosen Chen
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2361-2376
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 (31 October 2021) 
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Diabetes mellitus and postoperative blood glucose value help predict posthepatectomy liver failure in patients with hepatocellular carcinoma
Jianchen Luo, Liangliang Xu, Lian Li, Jingfu Zhang, Ming Zhang, Mingqing Xu
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2377-2387
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 (31 October 2021) 
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Hsa_circ_NOTCH3 regulates ZNF146 through sponge adsorption of miR-875-5p to promote tumorigenesis of hepatocellular carcinoma
Lei Bao, Min Wang, Qiqi Fan
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2388-2402
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 (31 October 2021) 
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Diagnostic role of contrast-enhanced ultrasonography versus conventional B-mode ultrasonography in cirrhotic patients with early hepatocellular carcinoma: a retrospective study
Yandong Jiang, Meng Zhang, Yanting Zhu, Dongxiao Zhu
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2403-2411
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 (31 October 2021) 
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Prognostic impact of lymphopenia and neutrophil-lymphocyte ratio for patients with anal squamous cell carcinoma
Brian De, Ethan B. Ludmir, Craig A. Messick, Matthew C. Cagley, Van K. Morris, Prajnan Das, Bruce D. Minsky, Cullen M. Taniguchi, Grace L. Smith, Eugene J. Koay, Albert C. Koong, Radhe Mohan, Emma B. Holliday
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2412-2422
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 (31 October 2021) 
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Molecular characterization of squamous cell carcinoma of the anal canal
Samantha A. Armstrong, Rita Malley, Hongkun Wang, Heinz-Josef Lenz, David Arguello, Wafik S. El-Deiry, Joanne Xiu, Zoran Gatalica, Jimmy J. Hwang, Philip A. Philip, Anthony F. Shields, John L. Marshall, Mohamed E. Salem, Benjamin A. Weinberg
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2423-2437
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 (31 October 2021) 
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Review Article

Narrative review of the role of yttrium-90 selective internal radiation therapy in the surgical management of colorectal liver metastases
Maitham A. Moslim, D. Rohan Jeyarajah
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2438-2446
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 (31 October 2021) 
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Editorial on Surgery for Locally Advanced Pancreatic Cancer1

Locally advanced pancreatic cancer—a resectable disease?
Elena B. Rangelova
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2447-2449
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 (31 October 2021) 
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Review Article on Surgery for Locally Advanced Pancreatic Cancer1

Resectable, borderline, and locally advanced pancreatic cancer—“the good, the bad, and the ugly” candidates for surgery?
Svein Olav Bratlie, Johanna Wennerblom, Caroline Vilhav, Jan Persson, Elena Rangelova
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2450-2460
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 (31 October 2021) 
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Neoadjuvant treatment of localized pancreatic adenocarcinoma
Alexis D. Leal, Wells A. Messersmith, Christopher H. Lieu
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2461-2474
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 (31 October 2021) 
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Selecting surgical candidates with locally advanced pancreatic cancer: a review for modern pancreatology
Y. H. Andrew Wu, Atsushi Oba, Ronggui Lin, Shuichi Watanabe, Cheryl Meguid, Richard D. Schulick, Marco Del Chiaro
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2475-2483
.
 (31 October 2021) 
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Favorable tumor biology in locally advanced pancreatic cancer—beyond CA19-9
Benedict Kinny-Köster, Joseph R. Habib, Christopher L. Wolfgang, Jin He, Ammar A. Javed
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2484-2494
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 (31 October 2021) 
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Extent of venous resection during pancreatectomy—finding the balance of technical possibility and feasibility
Atsushi Oba, Tomotaka Kato, Yosuke Inoue, Y. H. Andrew Wu, Yoshihiro Ono, Takafumi Sato, Hiromichi Ito, Akio Saiura, Yu Takahashi
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2495-2502
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 (31 October 2021) 
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Surgery for locally advanced pancreatic ductal adenocarcinoma—is it only about the vessels?
Max Heckler, Thilo Hackert
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2503-2511
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 (31 October 2021) 
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Pathology reporting of margin status in locally advanced pancreatic cancer: challenges and uncertainties
Eline C. Soer, Caroline S. Verbeke
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2512-2520
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 (31 October 2021) 
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How to select the most appropriate adjuvant treatment after neoadjuvant treatment and resection for locally advanced pancreatic cancer?
Elena Rangelova, Svein Olav Bratlie
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2521-2535
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 (31 October 2021) 
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Can local ablative techniques replace surgery for locally advanced pancreatic cancer?
Ulrike Heger, Thilo Hackert
Journal of Gastrointestinal Oncology  
2021;
12
(5)
:2536-2546
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 (31 October 2021) 
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Disclosure：

1. The series “Surgery for Locally Advanced Pancreatic Cancer” was commissioned by the Editorial office, Journal of Gastrointestinal Oncology without any sponsorship or funding. Elena Rangelova served as the unpaid Guest Editor for the series.