Most Read article list (ranking real-time pageviews since the publication of the article)

Original Article

Beyond microsatellite testing: assessment of tumor mutational burden identifies subsets of colorectal cancer who may respond to immune checkpoint inhibition

David A. Fabrizio, Thomas J. George Jr, Richard F. Dunne, Garrett Frampton, James Sun, Kyle Gowen, Mark Kennedy, Joel Greenbowe, Alexa B. Schrock, Aram F. Hezel, Jeffrey S. Ross, Phillip J. Stephens, Siraj M. Ali, Vincent A. Miller, Marwan Fakih, Samuel J. Klempner

Published online: 01 August 2018

PDF Pages: 610-617 Full Text (15775) Open Access

Review Article

Current and future systemic treatment options in metastatic pancreatic cancer

Cagatay Arslan, Suayib Yalcin

Published online: 22 August 2014

PDF Pages: 280-295 Full Text (15585) Open Access

Review Article

Quality of life and hepatocellular carcinoma

Shipra Gandhi, Sapna Khubchandani, Renuka Iyer

Published online: 22 August 2014

PDF Pages: 296-317 Full Text (15432) Open Access

Original Article

The inhibitory effects of probiotics on colon cancer cells: in vitro and in vivo studies

Fangjian Shang, Xia Jiang, Haobo Wang, Shihao Chen, Xin Wang, Ying Liu, Shang Guo, Dongyun Li, Weifang Yu, Zengren Zhao, Guiqi Wang

Published online: 30 December 2020

PDF Pages: 1224-1232 Full Text (15386) Reporting Checklist Data Sharing Statement COI Form Open Access

Special Review: Rectal Cancer-current Therapies and Emerging Concepts

Evolution of imaging in rectal cancer: multimodality imaging with MDCT, MRI, and PET

Siva P. Raman, Yifei Chen, Elliot K. Fishman

Published online: 13 April 2015

PDF Pages: 172-184 Full Text (15255) Open Access

Review Article

HIFU for palliative treatment of pancreatic cancer

Tatiana D. Khokhlova, Joo Ha Hwang

Published online: 01 September 2011

PDF Pages: 175-184 Full Text (15153) Open Access

Review Article

The complexity of the count: considerations regarding lymph node evaluation in colorectal carcinoma

Laura J. Denham, Justin C. Kerstetter, Paul C. Herrmann

Published online: 02 December 2012

PDF Pages: 342-352 Full Text (15179) Open Access

Review Article

Predictive and prognostic biomarkers in personalized gastrointestinal cancer treatment

Helena Verdaguer, Tamara Saurí, Teresa Macarulla

Published online: 23 June 2017

PDF Pages: 405-417 Full Text (15088) Open Access

Review Article (Current Strategies in Colon Cancer Management)

Surgical management of recurrent colon cancer

Kilian G. M. Brown, Cherry E. Koh

Published online: 27 June 2020

PDF Pages: 513-525 Full Text (15084) COI Form Open Access

Review Article

Surgical technology and pharmacology of hyperthermic perioperative chemotherapy

Paul H. Sugarbaker, Kurt Van der Speeten

Published online: 01 February 2016

PDF Pages: 29-44 Full Text (15087) Open Access

Review Article (Current Status of Colorectal Cancer Surgery)

Hepatic metastasis from colorectal cancer

Alfred Wei Chieh Kow

Published online: 17 December 2019

PDF Pages: 1274-1298 Full Text (14930) Open Access

Review Article

Metastatic colorectal cancer presenting with bone marrow metastasis: a case series and review of literature

Rita Assi, Deborah Mukherji, Ali Haydar, Maya Saroufim, Sally Temraz, Ali Shamseddine

Published online: 01 April 2016

PDF Pages: 284-297 Full Text (14828) Open Access

Original Article

Treatment of locally advanced unresectable pancreatic cancer: a 10-year experience

Nadia K Malik, Kilian Salerno May, Rameela Chandrasekhar, Wen Wee Ma, Leayn Flaherty, Renuka Iyer, John Gibbs, Boris Kuvshinoff, Gregory Wilding, Graham Warren, Gary Y Yang

Published online: 02 December 2012

PDF Pages: 326-334 Full Text (14802) Open Access

Editorial

Low prevalence of invasive adenocarcinoma and occult cancer on esophageal resection for Barrett’s esophagus with high-grade dysplasia: Evidence for conservative management

Deepa T Patil, Thomas P Plesec, John R Goldblum

Published online: 17 March 2011

PDF Pages: 5-7 Full Text (14745) Open Access

Review Article

Gastrointestinal lymphomas: Morphology, immunophenotype and molecular features

Marnelli A. Bautista-Quach, Christopher D. Ake, Mingyi Chen, Jun Wang

Published online: 01 September 2012

PDF Pages: 209-225 Full Text (14723) Open Access

Review Article

Primary pancreatic lymphoma: what we need to know

Neda Rad, Alireza Khafaf, Amir Houshang Mohammad Alizadeh

Published online: 13 August 2017

PDF Pages: 749-757 Full Text (14620) Open Access

Review Article

Health disparities in colorectal cancer among racial and ethnic minorities in the United States

Christian S. Jackson, Matthew Oman, Aatish M. Patel, Kenneth J. Vega

Published online: 02 April 2016

PDF Pages: S32-S43 Full Text (14603) Open Access

Review Article

Radiation therapy in the postoperative management of esophageal cancer

Salma K Jabbour, Charles R Thomas Jr

Published online: 13 December 2010

PDF Pages: 102-111 Full Text (14528) Open Access

Review Article

MicroRNAs and esophageal cancer

Santosh Kumar Patnaik, Reema Mallick, Sai Yendamuri

Published online: 13 September 2010

PDF Pages: 55-63 Full Text (14444) Open Access

Case Report

Mucinous adenocarcinoma of the appendix presenting as intussusception in 27 year old female

Ghulam Siddiqui, Seth Lipka, Lester Freedman, Umeko Takeshige, Kaleem Rizvon, Paul Mustacchia

Published online: 02 December 2012

PDF Pages: 369-372 Full Text (14494) Open Access

Review Article

The genomics and therapeutics of HER2-positive gastric cancer—from trastuzumab and beyond

Ciara M. Kelly, Yelena Y. Janjigian

Published online: 01 October 2016

PDF Pages: 750-762 Full Text (14075) Open Access

Original Article

A pilot study evaluating the safety and toxicity of epirubicin, cisplatin, and UFT (ECU regimen) in advanced gastric carcinoma

Sezer Saglam, N Faruk Aykan, Burak Sakar, Mine Gulluoglu, Emre Balik, Hasan Karanlik

Published online: 17 March 2011

PDF Pages: 19-26 Full Text (13948) Open Access

Review Articles

A review of cutaneous toxicities from targeted therapies in the treatment of colorectal cancers

Christopher Urban, Milan J. Anadkat

Published online: 11 September 2013

PDF Pages: 319-327 Full Text (13963) Open Access

Original Article

Evaluation and comparison of postoperative levels of serum bilirubin, serum transaminases and alkaline phosphatase in laparoscopic cholecystectomy versus open cholecystectomy

Rikki Singal, Rajinder Pal Singal, Karamjot Sandhu, Bir Singh, Gaurav Bhatia, Abhishek Khatri, Bhanu Pratap Sharma

Published online: 01 October 2015

PDF Pages: 479-486 Full Text (13771) Open Access

Original Article

Dose modification and efficacy of nab-paclitaxel plus gemcitabine vs. gemcitabine for patients with metastatic pancreatic cancer: phase III MPACT trial

Werner Scheithauer, Ramesh K. Ramanathan, Malcolm Moore, Teresa Macarulla, David Goldstein, Pascal Hammel, Volker Kunzmann, Helen Liu, Desmond McGovern, Alfredo Romano, Daniel D. Von Hoff

Published online: 01 June 2016

PDF Pages: 469-478 Full Text (13729) Open Access

Review Articles

Soft tissue tumors of the anorectum: rare, complex and misunderstood

Mohammed O. Nassif, Nora H. Trabulsi, Kelli M. Bullard Dunn, Ayoub Nahal, Ari-Nareg Meguerditchian

Published online: 22 March 2013

PDF Pages: 82-94 Full Text (13609) Open Access

Review Article

Endoscopic options for early stage esophageal cancer

Pari M. Shah, Hans Gerdes

Published online: 17 February 2015

PDF Pages: 20-30 Full Text (13526) Open Access

Review Article

Systematic review on quality of life outcomes after gastrectomy for gastric carcinoma

Bernard Shan, Leonard Shan, David Morris, Sanjeev Golani, Akshat Saxena

Published online: 01 October 2015

PDF Pages: 544-560 Full Text (13543) Open Access

Review Article

Emerging therapies in pancreas cancer

Adam Kotowski, Wen W Ma

Published online: 01 June 2011

PDF Pages: 93-103 Full Text (13414) Open Access

Review Article

Do all locally advanced rectal cancers require radiation? A review of literature in the modern era

David T Vonk, Lisa J Hazard

Published online: 13 September 2010

PDF Pages: 45-54 Full Text (13339) Open Access

Original Article

The localisation of cancer in the sigmoid, rectum or rectosigmoid junction using endoscopy or radiology—What is the most accurate method?

Ruud J. L. F. Loffeld, Marcel Flens, Gerwin Fransen, Frank C. den Boer, Aart van Bochove

Published online: 20 December 2014

PDF Pages: 469-473 Full Text (13217) Open Access

Review Article on Applying Tumor Genotyping and New Clinical Approaches to the Management of Colorectal Cancer

Implications of mismatch repair-deficient status on management of early stage colorectal cancer

Hisato Kawakami, Aziz Zaanan, Frank A. Sinicrope

Published online: 01 December 2015

PDF Pages: 676-684 Full Text (13109) Open Access

Review Article

Laparoscopic distal pancreatectomy for adenocarcinoma: safe and reasonable?

Lauren M. Postlewait, David A. Kooby

Published online: 01 August 2015

PDF Pages: 406-417 Full Text (Video) (13133) Open Access

Review Article

The promise of PD-1 inhibitors in gastro-esophageal cancers: microsatellite instability vs. PD-L1

Zhaohui Jin, Harry H. Yoon

Published online: 01 October 2016

PDF Pages: 771-788 Full Text (13006) Open Access

Review Article

Adjuvant chemoradiation for pancreatic cancer: what does the evidence tell us?

Michael D. Chuong, Drexell H. Boggs, Kruti N. Patel, William F. Regine

Published online: 30 June 2014

PDF Pages: 166-177 Full Text (12966) Open Access

Review Article

Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: a review of factors contributing to morbidity and mortality

Andrew D. Newton, Edmund K. Bartlett, Giorgos C. Karakousis

Published online: 01 February 2016

PDF Pages: 99-111 Full Text (12819) Open Access

Original Articles

Mismatch repair protein expression in colorectal cancer

Elrasheid A. H. Kheirelseid, Nicola Miller, Kah Hoong Chang, Catherine Curran, Emer Hennessey, Margaret Sheehan, Michael J Kerin

Published online: 26 December 2013

PDF Pages: 397-408 Full Text (12882) Open Access

Review Articles

The role of EGFR monoclonal antibodies (MoABs) cetuximab/panitumab, and BRAF inhibitors in BRAF mutated colorectal cancer

Shan Muhammad, Zheng Jiang, Zheng Liu, Kavanjit kaur, Xishan Wang

Published online: 22 March 2013

PDF Pages: 72-81 Full Text (12634) Open Access

Review Article

Human papillomavirus tumor infection in esophageal squamous cell carcinoma

Ethan B. Ludmir, Sarah J. Stephens, Manisha Palta, Christopher G. Willett, Brian G. Czito

Published online: 01 June 2015

PDF Pages: 287-295 Full Text (12671) Open Access

Original Article

Insulin caused drug resistance to oxaliplatin in colon cancer cell line HT29

Jiezhong Chen, Xu-Feng Huang, Liang Qiao, Andrew Katsifis

Published online: 17 March 2011

PDF Pages: 27-33 Full Text (12427) Open Access

Review Article

FDG PET imaging in the staging and management of gastric cancer

Shane Hopkins, Gary Y Yang

Published online: 17 March 2011

PDF Pages: 39-44 Full Text (12413) Open Access

Review Article

Neoadjuvant therapy for gastric cancer: current evidence and future directions

Andrew D. Newton, Jashodeep Datta, Arturo Loaiza-Bonilla, Giorgos C. Karakousis, Robert E. Roses

Published online: 01 October 2015

PDF Pages: 534-543 Full Text (12448) Open Access

Original Article

Molecular spectrum of KRAS, NRAS, BRAF, PIK3CA, TP53, and APC somatic gene mutations in Arab patients with colorectal cancer: determination of frequency and distribution pattern

Humaid O. Al-Shamsi, Jeremy Jones, Yazan Fahmawi, Ibrahim Dahbour, Aziz Tabash, Reham Abdel-Wahab, Ahmed O. S. Abousamra, Kenna R. Shaw, Lianchun Xiao, Manal M. Hassan, Benjamin R. Kipp, Scott Kopetz, Amr S. Soliman, Robert R. McWilliams, Robert A. Wolff

Published online: 09 December 2016

PDF Pages: 882-902 Full Text (12219) Open Access

Review Article

Technical aspects of radiation therapy for anal cancer

Eli D. Scher, Inaya Ahmed, Ning J. Yue, Salma K. Jabbour

Published online: 30 June 2014

PDF Pages: 198-211 Full Text (12142) Open Access

Review Articles

Cytopathology of the pancreatobiliary tract–the agony, and sometimes, the ease of it

Rachel Conrad, Shobha Castelino-Prabhu, Camilla Cobb, Anwar Raza

Published online: 19 June 2013

PDF Pages: 210-219 Full Text (12121) Open Access

Original Article

A combined treatment of curcumin, piperine, and taurine alters the circulating levels of IL-10 and miR-21 in hepatocellular carcinoma patients: a pilot study

Hala M. Hatab, Fatma F. Abdel Hamid, Ahmed F. Soliman, Tamer A. Al-Shafie, Yahia M. Ismail, Motawa E. El-Houseini

Published online: 01 August 2019

PDF Pages: 766-776 Full Text (12184) Open Access

Editorial

Splenectomy revisited in 2011: Impact on hematologic toxicities while performing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

Nancy Deslauriers, Harold Olney, Rami Younan

Published online: 01 June 2011

PDF Pages: 61-63 Full Text (12043) Open Access

Original Articles

Signature of microsatellite instability, KRAS and BRAF gene mutations in German patients with locally advanced rectal adenocarcinoma before and after neoadjuvant 5-FU radiochemotherapy

Melanie Demes, Stefanie Scheil-Bertram, Holger Bartsch, Annette Fisseler-Eckhoff

Published online: 19 June 2013

PDF Pages: 182-192 Full Text (12017) Open Access

Original Article

Bax expression is a candidate prognostic and predictive marker of colorectal cancer

Venkat R Katkoori, Catalina Suarez-Cuervo, Chandrakumar Shanmugam, Nirag C Jhala, Tom Callens, Ludwine Messiaen, James Posey III, Harvey L Bumpers, Sreelatha Meleth, William E Grizzle, Upender Manne

Published online: 13 December 2010

PDF Pages: 76-89 Full Text (12090) Open Access

Review Articles

Integrating anti-EGFR therapies in metastatic colorectal cancer

Sigurdis Haraldsdottir, Tanios Bekaii-Saab

Published online: 11 September 2013

PDF Pages: 285-298 Full Text (12072) Open Access