Vol 15, No 4 (August 31, 2024): Journal of Gastrointestinal Oncology

Original Article

Patterns of regional lymph node metastasis predict postoperative overall survival and disease-free survival in locally advanced esophageal squamous cell carcinoma
Haijie Xu, Shujie Huang, Jianrong Chen, Xirui Lin, Yuejiao Dong, Liangli Hong, Zefeng Xie, Hansheng Wu
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1365-1372
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 (31 August 2024) 
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Risk factors contributing to morbidity associated with feeding tubes placed for esophageal cancer patients undergoing esophagectomy: a single-center retrospective study
Ge Shi, Rahul Nayak, Richard Malthaner, Dalilah Fortin, Richard Inculet, Mehdi Qiabi
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1373-1385
.
 (31 August 2024) 
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Clinical features and risk of multiple primary malignancies after endoscopic treatment in patients with early esophageal squamous cell carcinoma: a retrospective cohort study
Haoxi Liu, Qian Zhang, Shutian Zhang, Yang Zhang, Ruyun Song, Peng Li, Jie Xing
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1386-1398
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 (31 August 2024) 
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Efficacy and safety of camrelizumab combined with chemotherapy in the first-line treatment of advanced gastric cancer: a single-arm, phase II study
Wenlou Liu, Hongmei Wang, Yang Zhao, Yan Ge, Juangjuang Tang, Menghan Cao, Silvio Matsas, Daniel Adam Breadner, Xiaobing Qin, Zhengxiang Han
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1399-1408
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 (31 August 2024) 
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Potential molecular metabolic mechanisms underlying the effects of cimifugin in gastric cancer through single-cell and bulk RNA sequencing combined with network pharmacology
Ziming Zhu, Yinbiao Zhang, Xinyue Zhang, Qiaoling Chen, Shanneng Tang, Xuan Zhou, Xiao Li, Jieying Wen, Yang Bai, Tao Zhang
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1409-1430
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 (31 August 2024) 
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CMTM4 inhibits gastric tumorigenesis and metastasis
Xiurui Han, Weiwei Fu, Qinghua Sun, Jing Ning, Jing Zhang, Silvio Matsas, Fabrício Freire de Melo, Hejun Zhang, Xinyu Hao, Qiao Meng, Yueqing Gong, Huiling Zheng, Jing Zhang, Shigang Ding
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1431-1445
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 (31 August 2024) 
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Developing a prognostic signature: identifying differentially expressed genes in cardia and non-cardia gastric cancer for immunity and therapeutic sensitivity analysis
Xianmin Li, Chong Zhou, Yindi Zhu, Wenjie Wang, Shuguang Han, Yicen Zou, Lian Lian, Kai Chen
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1446-1463
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 (31 August 2024) 
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Proteome-wide Mendelian randomization and single-cell sequencing analysis identify the association between plasma proteins and gastric cancer
Yichen Jin, Zilong Lei, Peixin Li, Guoruiyu Lyu
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1464-1474
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 (31 August 2024) 
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Parkinson’s disease and the risk of gastrointestinal cancers: a two-sample Mendelian randomization study
Zijin Liu, Lili Cui
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1475-1486
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 (31 August 2024) 
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Cultural and social barriers to hope in gastrointestinal cancer patients
Vera Qu, Caressa Hui, Zhihui Fang, Scott Jackson, Lucas Vitzthum, Elham Rahimy, Jennifer Hall, Erqi L. Pollom
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1487-1496
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 (31 August 2024) 
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Regorafenib combined with immune checkpoint inhibitors versus regorafenib monotherapy as a late-line treatment for metastatic colorectal cancer: a single-center, retrospective cohort study
Can Chen, Xi Luo, Wenhua Tang, Haofei Geng, Julia Martínez-Pérez, Timothy Price, Lili Kang, Honglian Lu, Yanling Zhang
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1497-1507
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 (31 August 2024) 
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The impact of transanal drainage tube on the incidence of anastomotic leakage and small bowel obstruction in radical surgery (Dixon) for rectal cancer: a retrospective cohort study
Zihao Wang, Huachi Li, Haoran Tao, Min Xie, Shaozhong Wei, Zhiguo Xiong
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1508-1518
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 (31 August 2024) 
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Fruquintinib in metastatic colorectal cancer: a multicenter real-world analysis on efficacy, safety, and predictive and prognostic factors
Yi Wang, Jianfen Xu, Mingjun Dong, Kaitai Liu, Yi Lu, Ke Chen, Yuepeng Cao, Hang Shi, Yanping Bei, Jianjiong Li, Jianpei Zhao, Yisheng Cao, Ning Lu, Lu Yang, Haizhong Liu, Ping Cai, Kai Li, Tong Yang, Ning He, Jing Dong, Chen Zhang
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1519-1533
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 (31 August 2024) 
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PD-1 blockade combined with chemotherapy and bevacizumab in DNA mismatch repair-proficient/microsatellite stable colorectal liver metastases
Qianqian Men, Yinghua Duan, Fengyun Pei, Qijun Yao, Wan He, Yandong Zhao, Lishuo Shi, Guangjian Liu, Jun Huang
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1534-1544
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 (31 August 2024) 
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Differential effect of tumor budding on the benefit of adjuvant chemotherapy in stage II colorectal cancer: a retrospective observational study
Xin Ran, Yan Chen, Chengxiang Liu, He Xiao, Xiaona Su, Zhuo Chen, Jia Du, Juan He, Peng Zhong, Mengxia Li, Nan Dai, Chuan Chen
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1545-1555
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 (31 August 2024) 
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Association between sleep traits and risk of colorectal cancer: a bidirectional Mendelian randomization study
Fan He, Fuyu Yang, Chenglin Tang, Defei Chen, Junjie Xiong, Yu Zou, Dongqin Zhao, Dong Peng, Kun Qian
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1556-1567
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 (31 August 2024) 
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The benefit of adjuvant chemotherapy in pathological T1–3N0M0 rectal mucinous adenocarcinoma: no improvement survival outcomes based on long-term survival analysis of large population data
Hualin Liao, Tengyu Zeng, Xianqiang Xie, Jiyang Li, Dongsheng Li, Kejin Yan, Fan Chen, Hongliang Zhu
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1568-1579
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 (31 August 2024) 
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Integrated molecular profiling of RAS, BRAF mutations, and mismatch repair status in advanced colorectal carcinoma: insights from gender and tumor laterality
Gabriela Remonatto, Emily Ferreira Salles Pilar, Fernanda de-Paris, Pedro Guilherme Schaefer, Lúcia Maria Kliemann
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1580-1591
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 (31 August 2024) 
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A novel model based on protein post-translational modifications comprising the immune landscape and prediction of colorectal cancer prognosis
Tianyu Yu, Jun Yan, Chang Liu, Chengzhi Yao, Yuhang Xu, Jiarui Xu, Jiaxi Xu, Qi Sun
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1592-1612
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 (31 August 2024) 
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Promotion of hepatocellular carcinoma stemness and progression by abnormal spindle-like microcephaly-associated protein via the Wnt/β-catenin pathway
Gao-Jie Li, Ying Xiang, Ji-Yao Yang, Ralf Weiskirchen, Ruo Feng, Wen-Long Zhai
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1613-1626
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 (31 August 2024) 
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Efficacy and safety of transarterial chemoembolization alone compared to its combination with anlotinib among patients with intermediate or advanced stage hepatocellular carcinoma: a phase II randomized controlled trial
Dinghu Zhang, Zhewei Zhang, Jun Luo, Jiaping Zheng, Xiaochun Mao, Diamantis I. Tsilimigras, Ho Jong Chun, Hui Zeng
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1627-1635
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 (31 August 2024) 
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Identification of a lactylation-related gene signature to characterize subtypes of hepatocellular carcinoma using bulk sequencing data
Yan Chen, Li Chang, Ling Hu, Cuiping Yan, Liu Dai, Vishal G. Shelat, Hooman Yarmohammadi, Jun Sun
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1636-1646
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 (31 August 2024) 
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Identification of a prognostic disulfidptosis-related gene signature in hepatocellular cancer
Jinhong Zhu, Yan Wu, Pengyu Ji, Jun Qi, Xuekun Yang, Christine Pocha, Francisco Tustumi, Tiago Biachi de Castria
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1647-1656
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 (31 August 2024) 
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Development and validation of a nomogram to predict cancer-specific survival of patients with large hepatocellular carcinoma accepting surgical resection: a real-world analysis based on the SEER database
Luyang Li, Chengli Liu, Haoming Li, Jun Yang, Meng Pu, Shuhan Zhang, Yingbo Ma
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1657-1673
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 (31 August 2024) 
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NOVA2 regulates the properties of liver cancer stem cells and lenvatinib resistance in hepatocellular carcinoma via the Wnt pathway
Jing-Zhu Cao, Chao-Qun Wang, Zheng Shi, Jing-Yun Song, Francisco Tustumi, Tiago Biachi de Castria, Jennifer Wu, Christine Pocha, Diamantis I. Tsilimigras, Zhi-Hong Wang, Tao Tao, Jin Lu
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1674-1685
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 (31 August 2024) 
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The clinical outcomes of patients with vascular invasion after deceased donor liver transplantation
Zhaodan Ye, Li Zhuang, Xiangyan Liu, Mengchen Song, Jingfeng Zhang, Guohong Cao
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1686-1697
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 (31 August 2024) 
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Discontinuation of immune checkpoint inhibitors in hepatocellular carcinoma: a retrospective cohort study
Liuyu Zhou, Yuhong Zhang, Jie Zheng, Minghao Ruan, Jin Zhang, Yao Li, Riming Jin, Dong Wu, Hanyong Sun, Jianjun Zhang, Ruoyu Wang
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1698-1711
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 (31 August 2024) 
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YAP-based nomogram predicts poor prognosis in patients with hepatocellular carcinoma after curative surgery
Wenxuan Zhou, Feiyang Ye, Gaowei Yang, Chenghu Liu, Zeya Pan, Chengjing Zhang, Hui Liu
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1712-1722
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 (31 August 2024) 
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Liquid-liquid phase separation-related features of PYGB/ACTR3/CCNA2/ITGB1/ATP8A1/RAP1GAP2 predict the prognosis of pancreatic cancer
Xiaofeng Li, Ranran Yu, Baochang Shi, Akhil Chawla, Xianguang Feng, Kai Zhang, Li Liang
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1723-1745
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 (31 August 2024) 
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LDHA as a predictive biomarker and its association with the infiltration of immune cells in pancreatic adenocarcinoma
Qiuqing Zheng, Yingjun Xie, Luyin Xu, Delian Chen, Jianfeng Wu, Shuxun Liu, Lili Wu, Peiwei Fang, Fajun Xie
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1746-1759
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 (31 August 2024) 
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Analyzing the role of TM4SF1 expression in pancreatic adenocarcinoma: understanding prognostic implications and therapeutic opportunities
Dong Xu, Mingguang Jia, Fei Yang, Xiaohui Zhang, Kuirong Jiang
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1760-1776
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 (31 August 2024) 
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Epidemiology, survival and new treatment modalities for intrahepatic cholangiocarcinoma
Yating Wang, Yasir Alsaraf, Sai Samyuktha Bandaru, Susan Lyons, Leo Reap, Tra Ngo, Zhiyong Yu, Qian Yu
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1777-1788
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 (31 August 2024) 
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Pancreatic cancer mortality trends in the United States: how much have we moved the needle?
Jia Yi Tan, Yong Hao Yeo, Wern Lynn Ng, Cho Han Chiang, Chee-Chee Stucky, Nabil Wasif, Zhi Ven Fong
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1789-1795
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 (31 August 2024) 
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Sarcomatoid change in combined hepatocellular carcinoma and cholangiocarcinoma as a poor prognostic factor
Suk Won Lee, Milim Kim, Sung Hyun Kim, Dai Hoon Han, Gi Hong Choi, Kyung Sik Kim, Jin Sub Choi, Young Nyun Park
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1796-1804
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 (31 August 2024) 
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Combination of neutrophil-to-lymphocyte ratio and serum CA 19-9 as a prognostic factor in pancreatic cancer
Juan Sebastián García-Herrera, Wendy R. Muñoz-Montaño, Horacio N. López-Basave, Flavia Morales-Vásquez, Carolina Castillo-Morales, Luis G. Rivera-Mogollán, Karla F. Hernández-Castañeda
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1805-1819
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 (31 August 2024) 
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Concomitant or antecedent intraductal papillary mucinous neoplasm is not a prognostic factor in resected pancreatic cancer
Pedro Luiz Serrano Uson Junior, Ana Luiza Spina Nagy, Igor Wanderley Reis Dias, Marcelo Bruno de Rezende, Roberto Pestana, Diogo Bugano, Francisco Tustumi, Guilherme Naccache Namur, Jaime Arthur Pirola Kruger, Alberto Goldenberg, Sergio Eduardo Alonso Araujo, Nam Jin Kim, Sidney Klajner, Mitesh Borad, Fernando Moura
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1820-1826
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 (31 August 2024) 
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Laparoscopic distal pancreatectomy for pancreatic cancer: an overview of evaluation and treatment strategies
Domenech Asbun, John A. Stauffer, Horacio J. Asbun
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1827-1835
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 (31 August 2024) 
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Single-cell analysis of chemotherapy-resistant microenvironment identifies a chemo-response biomarker for pancreatic cancer
Ruiling Xu, Jing Shao, Jingyang Liu, Bo Qu, Jing Liu
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1836-1846
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 (31 August 2024) 
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Intra-abdominal temperature variation during hyperthermic intraperitoneal chemotherapy evaluated via computational fluid dynamics modeling
Olivia S. Cooney, Dylan A. Goodin, Tyler J. Mouw, Robert C. G. Martin, Hermann B. Frieboes
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1847-1860
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 (31 August 2024) 
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Review Article

Particle therapy in gastrointestinal cancer—a narrative review
Matthias Mattke
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1861-1869
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 (31 August 2024) 
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The emerging role of FAM46C as a biomarker and therapeutic target in gastric adenocarcinoma
Shelly Luu, Ning Fu, Paul Savage, Karina Pacholczyk, Taylor Zaslavsky, James Conner, Carol J. Swallow
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1870-1879
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 (31 August 2024) 
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Stereotactic body radiation therapy (SBRT) in patients with hepatocellular cancer—a narrative review and expert opinion
Sabine Gerum, Brane Grambozov, Falk Roeder
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1880-1892
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 (31 August 2024) 
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MR-linac based radiation therapy in gastrointestinal cancers: a narrative review
Jonas Ristau, Juliane Hörner-Rieber, Stefan A. Körber
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1893-1907
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 (31 August 2024) 
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Stereotactic body radiation therapy in non-liver colorectal metastases: a scoping review
Maria Ausilia Teriaca, Maria Massaro, Ciro Franzese, Tiziana Comito, Marta Scorsetti
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1908-1916
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 (31 August 2024) 
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Stereotactic body radiation therapy for colorectal cancer liver metastases
Jelena Lukovic, Laura A. Dawson
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1917-1925
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 (31 August 2024) 
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Case Report

Laparoscopic two-step abdomino-parasacral resection of a giant pelvic lipoma: a case report
Yurong Jiao, Federico Maria Mongardini, Hui Liu, Michele Cricrì, Haiting Xie, Ludovico Docimo, Jun Li
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1926-1932
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 (31 August 2024) 
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Spontaneous regression of advanced hepatocellular carcinoma following COVID-19 infection and vaccination: a case report and review of literature
Cody Eslinger, Pedro Luiz Serrano Uson Jr, Bolni Marius Nagalo, Mitesh J. Borad
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1933-1938
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 (31 August 2024) 
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The rare occurrence of unifocal peritoneal mesothelioma: a case report, literature review, and future directions
Shadin Ghabra, Aaron J. Dinerman, Collin A. Sitler, Diane Ahn, Stacy R. Joyce, Audra Satterwhite, Molly A. Sullivan, Andrew M. Blakely
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1939-1947
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 (31 August 2024) 
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Corticosteroid-dependent immune checkpoint inhibitor-induced enterocolitis treated with vedolizumab: a case report
Da-Long Wan, Chen Hu, Qing-Hong Ke, Tanyang Zhou, Linxiang Ruan, Hui Tang, Yan Shen
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1948-1956
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 (31 August 2024) 
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DNA signature and occult blood in stool led to diagnosis of an early-onset metastatic rectal cancer in a young pregnant woman: a case report
Josef van Helden, Moritz Eidens, Jürgen Fuhrländer, Ralf Weiskirchen, Dagfinn Øgreid
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1957-1961
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 (31 August 2024) 
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Response to hepatic arterial infusion chemotherapy combined with camrelizumab and targeted therapy in advanced primary hepatic neuroendocrine carcinoma: a case report and literature review
Xianmao Shi, Ze Su, Zhiyin Liang, Xing Sun, Jinwu Luo, Zhongrong Long, Hongmian Jiang, Jonathan Strosberg, Ravi Kumar Paluri, Yi Xiao
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1962-1972
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 (31 August 2024) 
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Case Report: iMDT Corner

Tumor complete response and pyogenic liver abscess secondary to concurrent microwave ablation plus atezolizumab and bevacizumab in liver cancer: a case report
Zhiqiang Sun, Lu Liu, Mingguang Xin, Jian Chen, Xiaoyu Chen, Jiale Cheng, Ho Jong Chun, Driss Raissi, Chengyi Jiang
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1973-1980
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 (31 August 2024) 
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Editorial Commentary

Transverse colon cancer: a call for focused research in an understudied heterogenous disease
Christopher Cann, Efrat Dotan
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1981-1986
.
 (31 August 2024) 
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PLK1 and its role in the evolving landscape of KRAS-mutated colorectal cancer
Harry Harvey, Eric Xueyu Chen
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1987-1992
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 (31 August 2024) 
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Gut microbiota modulation: the key to improving outcomes after colorectal cancer surgery?
Jack A. Helliwell, David G. Jayne
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1993-1995
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 (31 August 2024) 
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Mutant KRAS inhibitors enter the scene of precision therapeutics for pancreatic cancer
Gareth Pollin, Gwen A. Lomberk, Angela J. Mathison, Michael T. Zimmermann, Raul Urrutia
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:1996-2001
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 (31 August 2024) 
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MRTX1133’s promise for treating KRASG12D-mutant pancreatic cancer
Malak Haidar, Patrick Jacquemin
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:2002-2005
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 (31 August 2024) 
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Editorial

Another hammer, but we need a wrench, and a screwdriver—positron emission tomography/magnetic resonance imaging represents another tool for post-delivery 90Y dosimetry, but what are we still missing?
Gregory Woodhead, Shamar Young
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:2006-2010
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 (31 August 2024) 
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PD-L1 expression in pancreaticobiliary adenosquamous carcinoma: a potential biomarker for immunotherapy
Himil Mahadevia, Hani M. Babiker
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:2011-2012
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 (31 August 2024) 
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Modern times call for modernized treatment strategies for advanced gastrointestinal stromal tumors
Shruthi R. Perati, Andrew M. Blakely
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:2013-2015
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 (31 August 2024) 
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Duodenal neuroendocrine tumors: how safe is endoscopic resection?
Ji Yoon Yoon, Satish Nagula, Michelle Kang Kim
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:2016-2018
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 (31 August 2024) 
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Exploring the complexities of metachronous primary tumors after surgically managed pancreatic cancer—why lightning strikes twice
Jared Mount, John A. Stauffer
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:2019-2021
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 (31 August 2024) 
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Letter to the Editor

Effect of perioperative blood transfusion (BTF) on elderly gastric cancer patients
Jinqiang Liu, Kunli Du, Rui Zhang, Wei Zhou, Gaozan Zheng, Pengfei Wang, Jianyong Zheng, Fan Feng
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:2022-2023
.
 (31 August 2024) 
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Impact of perioperative blood transfusion on elderly gastric cancer patients
Mingyu Zhang, Qingbo Feng, Maijian Wang
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:2024-2025
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 (31 August 2024) 
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Insights and recommendations for enhancing the prognostic nomogram in elderly patients with stage II–III colorectal cancer
Yunlong Dai, Qingbo Feng
Journal of Gastrointestinal Oncology  
2024;
15
(4)
:2026-2027
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 (31 August 2024) 
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