Vol 13, No 6 (December 28, 2022) - Journal of Gastrointestinal Oncology

Original Article

Outcomes of patients with esophageal cancer after allogeneic hematopoietic stem cell transplantation

Ram Vasudevan Nampoothiri, Jonathan Yeung, Andrew Pierre, Rebecca Wong, Gail Darling, John Kim, Lillian L. Siu, Eric Chen, Elaine Bouttell, Jennifer Knox, Dennis (Dong Huan) Kim, Jeffrey H. Lipton

PDF Pages: 2705-2712 Full Text (1081) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Does chemotherapy regimen matter in the neoadjuvant treatment of esophageal cancer?

Shankar Logarajah, Prashan Jeyarajah, Muhammad Darwish, Maitham Moslim, Michael Jureller, Houssam Osman, D. Rohan Jeyarajah

PDF Pages: 2713-2720 Full Text (950) Reporting Checklist Data Sharing Statement COI Form Open Access

Early prediction of residual disease after neoadjuvant chemoradiotherapy and cetuximab for locally advanced esophageal cancer using ¹⁸F-FDG PET-CT imaging: a prospective cohort study

Baruch Brenner, Yulia Kundel, Zoya Cohen, Hadar Brand, Noa Gordon, Aaron Sulkes, Sara Morgenstern, Nikolai Menasherov, Hanoch Kashtan, David Groshar, Liran Domachevsky, Hanna Bernstine

PDF Pages: 2721-2735 Full Text (823) Reporting Checklist Data Sharing Statement COI Form Open Access

The role of adjuvant chemotherapy after neoadjuvant chemotherapy or chemoradiotherapy plus esophagectomy in patients with esophageal cancer: a retrospective cohort study

Hongbo He, Peng Zhang, Feng Li, Donglei Liu, Kai Wu

PDF Pages: 2736-2748 Full Text (1283) Reporting Checklist Data Sharing Statement COI Form Open Access

Application value of continuous seromuscular layer sutures in the reinforcement of esophagojejunostomy in total gastrectomy for gastric cancer: a retrospective comparative cohort study

Hailiang Fan, Dong Wang, Pingan Ding, Xinyu Yuan, Qun Zhao, Zhidong Zhang, Xuefeng Zhao, Bibo Tan, Yu Liu, Yong Li, Zetian Chen

PDF Pages: 2749-2757 Full Text (974) Reporting Checklist Data Sharing Statement COI Form Open Access

Pembrolizumab combined with paclitaxel and platinum as induction therapy for locally advanced esophageal squamous cell carcinoma: a retrospective, single-center, three-arm study

Wenbao Lin, Yangyun Huang, Lihuan Zhu, Wujin Li, Lilan Zhao, Xiaojie Pan, Jinlan Lin, Tianxing Guo

PDF Pages: 2758-2768 Full Text (1415) Reporting Checklist Data Sharing Statement COI Form Open Access

Risk factors and efficacy outcomes of early-onset severe neutropenia due to paclitaxel or nanoparticle albumin-bound paclitaxel combined with ramucirumab in advanced gastric cancer: a multicenter retrospective cohort study

Yuya Hagiwara, Akio Nakasya, Toshihiko Matsumoto, Tatsuki Ikoma, Yoshiyuki Yamamoto, Yusuke Kurioka, Takao Tsuduki, Takeshi Kajiwara, Tomohiro Nishina, Natsumi Yamashita, Toshikazu Moriwaki, Ichinosuke Hyodo

PDF Pages: 2769-2778 Full Text (1285) Reporting Checklist Data Sharing Statement COI Form Open Access

Immune-related adverse events and prognosis in patients with upper gastrointestinal cancer treated with nivolumab

Yoshihiro Hara, Yoshifumi Baba, Tasuku Toihata, Kazuto Harada, Katsuhiro Ogawa, Masaaki Iwatsuki, Shiro Iwagami, Yuji Miyamoto, Naoya Yoshida, Hideo Baba

PDF Pages: 2779-2788 Full Text (994) Reporting Checklist Data Sharing Statement COI Form Open Access

Obstructive sleep apnea and the incidence and mortality of gastrointestinal cancers: a systematic review and meta-analysis of 5,120,837 participants

Yao Hao Teo, Benjamin Kye Jyn Tan, Nicole Kye Wen Tan, Dominic Wei Ting Yap, Yi Xuen Chai, Yao Neng Teo, Ching-Hui Sia, Raghav Sundar, Emile Tan, Anna See, Song Tar Toh

PDF Pages: 2789-2798 Full Text (1634) Reporting Checklist COI Form Open Access

Decitabine enhances the tumoricidal potential of TRAIL via the epigenetic regulation of death receptor 4 in gastric cancer

Lin Li, Qian Niu, Yuanmin Zhu, Biao Fan, Guibin Yang

PDF Pages: 2799-2808 Full Text (925) Reporting Checklist Data Sharing Statement COI Form Open Access

Long non-coding RNA CNALPTC1 promotes gastric cancer progression by regulating the miR-6788-5p/PAK1 pathway

Fang Li, Bibo Tan, Zihao Chen, Qun Zhao, Shi Li, Pingan Ding, Chang Liu, Xiaoxiao Wang, Xiaoya Li, Yong Li

PDF Pages: 2809-2822 Full Text (813) Reporting Checklist Data Sharing Statement COI Form Open Access

Knockdown of carboxypeptidase A4 (CPA4) inhibits gastric cancer cell progression via cell cycle arrest and apoptosis

Xinyi Lei, Dong Liu, Danjun Song, Jun Fan, Gaiguo Dai, Litao Yang

PDF Pages: 2823-2831 Full Text (1110) Reporting Checklist Data Sharing Statement COI Form Open Access

LncRNA NORAD mediates KMT2D expression by targeting miR-204-5p and affects the growth of gastric cancer

Xinqi Chen, Ting Pan, Guohu Guo, Guohao Chen, Yongchang Cai, Yuxin Tang, Yijun Wang, Yucheng Wang, Zhenwei Deng, Libo Li, Yan Zhou

PDF Pages: 2832-2844 Full Text (975) Reporting Checklist Data Sharing Statement COI Form Open Access

Prognostic value of nicotinamide adenine dinucleotide (NAD⁺) metabolic genes in patients with stomach adenocarcinoma based on bioinformatics analysis

Linkun Cai, Chuanfeng Ke, Zikai Lin, Yalan Huang, Aling Wang, Shiying Wang, Chunhui Chen, Cailing Zhong, Lingyu Fu, Peixin Hu, Jiwei Chai, Haiyan Zhang, Beiping Zhang

PDF Pages: 2845-2862 Full Text (1256) Reporting Checklist COI Form Open Access

Comparison of efficacy and safety between endoscopic and laparoscopic resections in the treatment of gastric stromal tumors: a systematic review and meta-analysis

Yong-Qing Wang, Long-Quan Li, Guang-Ming Li

PDF Pages: 2863-2873 Full Text (923) Reporting Checklist COI Form Open Access

Efficacy and safety of camrelizumab plus chemotherapy versus chemotherapy alone in patients with untreated, HER2-negative, unresectable locally advanced, or metastatic gastric cancer or gastroesophageal junction cancer: a retrospective comparative cohort study

Jinyu Xiang, Wenjing Gong, Ping Sun, Xuan Wang, Aina Liu

PDF Pages: 2874-2884 Full Text (1285) Reporting Checklist Data Sharing Statement COI Form Open Access

The hsa_circ_0007396-miR-767-3p-CHD4 axis is involved in the progression and carcinogenesis of gastric cancer

Yantao Wang, Xuan Huang, Panpan Wang, Yi Zeng, Guozhi Zhou

PDF Pages: 2885-2902 Full Text (1267) Reporting Checklist Data Sharing Statement COI Form Open Access

Prognostic value of desmoplastic stromal reaction, tumor budding and tumor-stroma ratio in stage II colorectal cancer

Shuxuan Fan, Xiaonan Cui, Lei Zheng, Wenjuan Ma, Sunyi Zheng, Jing Wang, Lisha Qi, Zhaoxiang Ye

PDF Pages: 2903-2921 Full Text (1536) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Racial disparities and standard treatment in locally advanced rectal cancer: a National Cancer Database study

April Vassantachart, Michael Marietta, Shahil Mehta, Eugene Lin, Shelly X. Bian

PDF Pages: 2922-2937 Full Text (966) Reporting Checklist Peer Review File COI Form Open Access

A phase II randomized double blinded trial evaluating the efficacy of curcumin with pre-operative chemoradiation for rectal cancer

Jillian R. Gunther, Awalpreet S. Chadha, Sushovan Guha, Gottumukkala S. Raju, Dipen M. Maru, Mark F. Munsell, Yan Jiang, Peiying Yang, Edd Felix, Marilyn Clemons, Geena George Mathew, Pankaj K. Singh, John M. Skibber, Miguel A. Rodriguez-Bigas, George J. Chang, Cathy Eng, Marc E. Delclos, Christopher H. Crane, Prajnan Das, Sunil Krishnan

PDF Pages: 2938-2950 Full Text (2424) Reporting Checklist Trial Protocol Data Sharing Statement COI Form Open Access

Rectal tumor fragmentation as a response pattern following chemoradiation

Matthew N. Mills, Afrin Naz, Julian Sanchez, Sophie Dessureault, Iman Imanirad, Gregory Lauwers, Michelle Moore, Sarah Hoffe, Jessica Frakes, Seth Felder

PDF Pages: 2951-2962 Full Text (1254) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Effects of sevoflurane and propofol on postoperative nausea and vomiting in patients with colorectal cancer placed under general anesthesia: a systematic review and meta-analysis

Liping Wu, Yizhen Li, Junli Si

PDF Pages: 2963-2972 Full Text (1172) Reporting Checklist COI Form Open Access

Clinical study on risk factors related to postoperative recurrence or metastasis of rectal cancer: a retrospective cohort study

Huipeng Wang, Runqi Hong, Gengming Niu, Zhiqing Hu, Chongwei Ke

PDF Pages: 2973-2988 Full Text (1125) Reporting Checklist Data Sharing Statement COI Form Open Access

PRRX1 promotes colorectal cancer stemness and chemoresistance via the JAK2/STAT3 axis by targeting IL-6

Longzhu Zhong, Wanlin Tan, Qianqiong Yang, Zhaowei Zou, Rui Zhou, Yongsheng Huang, Zhenghua Qiu, Kehong Zheng, Zonghai Huang

PDF Pages: 2989-3008 Full Text (1309) Reporting Checklist Data Sharing Statement COI Form Open Access

A study of gene variation in All-RAS wild-type metastatic colorectal cancer and its correlation with cetuximab

Huimin Tao, Meng Shen, Xiaochang Zhang, Minghui Wang, Yan Wu, Hui Sun, Chen Ling, Ying Yang, Kai Chen, Dapeng Li

PDF Pages: 3009-3024 Full Text (1316) Reporting Checklist Data Sharing Statement COI Form Open Access

Comprehensive analysis of the correlation between GSTM1 and tumor immunity in colon cancer

Hao-Yun Luo, Wen-Lian Tang, Ling Xiang, Ling-Long Peng, Da-Bin Wu, Zhi-Yong Zhu, Hai-Tao Gu, Yun-Hao Tang, R. Serene Perkins, Hai-Ying Shen, Ya-Xu Wang

PDF Pages: 3025-3037 Full Text (1229) Reporting Checklist COI Form Open Access

Identification of genes and cellular response factors related to immunotherapy response in mismatch repair-proficient colorectal cancer: a bioinformatics analysis

Wenxiu Xue, Jinglong Shi

PDF Pages: 3038-3055 Full Text (1313) Reporting Checklist COI Form Open Access

Screening and identification of hub gene and differential gene and mutation sequence analysis of related genes in colorectal cancer based on bioinformatics analysis

Xiaofei Zhang, Leichang Zhang, Jian Lai, Yan Lu, Jianming Ye, Ying Wang

PDF Pages: 3056-3066 Full Text (1391) Reporting Checklist COI Form Open Access

Expression and clinical significance of miR-17-5p in tumor tissues of patients with colorectal cancer

Zheng Liu, Mengmeng Ji, Fangtong Jin, Feng Jiang, Xiaoping Liu

PDF Pages: 3067-3079 Full Text (1141) Reporting Checklist Data Sharing Statement COI Form Open Access

The prognostic role of fasting plasma glucose levels on survival in advanced colorectal cancer patients with type II diabetes mellitus: a retrospective cohort study

Qianhao Meng, Yuanyuan Yu, Ke Wang, Zicheng Zhang, Jian Zhao, Yusheng Wang, Dapeng Hao, Guangyu Wang

PDF Pages: 3080-3089 Full Text (1161) Reporting Checklist Data Sharing Statement COI Form Open Access

Circ_0000799 promotes proliferation and invasion in colorectal cancer and epithelial-mesenchymal transition

Chang-Hui Geng, Xue-Song Zhang, Miao He, Ping Gao, Hong-Wei Zhao

PDF Pages: 3090-3099 Full Text (809) Reporting Checklist Data Sharing Statement COI Form Open Access

Plasminogen activator, urokinase enhances the migration, invasion, and proliferation of colorectal cancer cells by activating the Src/ERK pathway

Yuanyi Ding, Wenbo Niu, Xiaochuan Zheng, Chaoxi Zhou, Guanglin Wang, Yun Feng, Bin Yu

PDF Pages: 3100-3111 Full Text (1047) Reporting Checklist Data Sharing Statement COI Form Open Access

The miRNA125a-5p and miRNA125b-1-5p cluster induces cell invasion by down-regulating DDB2-reduced epithelial-to-mesenchymal transition (EMT) in colorectal cancer

Fang Zhu, Juan Wei, Danni He, Jing He, Ling Liu, Huyang Hou, Hengmei Shi, Shidai Jin, Jun Li, Xiaoyan Shi, Ping Liu, Mao Huang

PDF Pages: 3112-3122 Full Text (921) Reporting Checklist Data Sharing Statement COI Form Open Access

Liver resection for hepatocellular carcinoma beyond the BCLC: are multinodular disease, portal hypertension, and portal system invasion real contraindications?

Andrea Zaidan de Almeida Barros, Gilton Marques Fonseca, Jaime Arthur Pirola Kruger, Fabricio Ferreira Coelho, Paulo Herman

PDF Pages: 3123-3134 Full Text (1026) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Molecular subtyping and IMScore based on immune-related pathways, oncogenic pathways, and DNA damage repair pathways for guiding immunotherapy in hepatocellular carcinoma patients

Zeyan Yu, Olivier Vyungura, Yinnong Zhao

PDF Pages: 3135-3153 Full Text (1085) Reporting Checklist COI Form Open Access

Comprehensive analysis of an autophagy-related prognostic model for predicting survival based on TCGA and ICGC database in hepatocellular carcinoma patients

Li-Na An, Lei Du, Liang-Liang Wang, Jing Chen, Xin-Rui Wang, Jian-Ping Duan

PDF Pages: 3154-3168 Full Text (1333) Reporting Checklist COI Form Open Access

Constructing and validating of m7G-related genes prognostic signature for hepatocellular carcinoma and immune infiltration: potential biomarkers for predicting the overall survival

Pulin Liu, Chengda Dong, Hongshuo Shi, Zhaojun Yan, Junlong Zhang, Jianmin Liu

PDF Pages: 3169-3182 Full Text (1053) Reporting Checklist COI Form Open Access

Gelatin sponge microparticles for transarterial chemoembolization combined with regorafenib in hepatocellular carcinoma: a single-center retrospective study

Mao Su, Songbai Chen, Shengmin Li, Fang Xu, Guangsheng Zhao, Junjie Qu, Jun Zhou

PDF Pages: 3183-3192 Full Text (1101) Reporting Checklist Data Sharing Statement COI Form Open Access

Identification of characteristic markers correlated with Th2 cell infiltration and metabolism molecular subtype in pancreatic adenocarcinoma

Zi-Jin Xu, Peng-Cheng Li, Wen-Quan Wang, Liang Liu

PDF Pages: 3193-3206 Full Text (1422) Reporting Checklist COI Form Open Access

Chemotherapy is associated with improved survival in a national cohort of stage IV pancreatic adenosquamous carcinoma

Ellery Altshuler, Andrea N. Riner, Kelly M. Herremans, Thomas J. George, Sherise C. Rogers, Alessandro Paniccia, Steven J. Hughes, Jesus C. Fabregas, Ibrahim Nassour

PDF Pages: 3207-3215 Full Text (960) Reporting Checklist Peer Review File COI Form Open Access

A phase II trial of GSK2256098 and trametinib in patients with advanced pancreatic ductal adenocarcinoma

Kyaw L. Aung, Elaine McWhirter, Stephen Welch, Lisa Wang, Sophia Lovell, Lee-Anne Stayner, Saara Ali, Anne Malpage, Barbara Makepeace, Makilpriya Ramachandran, Gun Ho Jang, Steven Gallinger, Tong Zhang, Tracy L. Stockley, Sandra E. Fischer, Neesha Dhani, David Hedley, Jennifer J. Knox, Lillian L. Siu, Rachel Goodwin, Philippe L. Bedard

PDF Pages: 3216-3226 Full Text (1593) Reporting Checklist Data Sharing Statement COI Form Open Access

Adjuvant treatment for the elderly patient with resected gallbladder cancer: a SEER-Medicare analysis

Elise de Savornin Lohman, Ali Belkouz, Usha Nuliyalu, Bas Groot Koerkamp, Heinz-Josef Klümpen, Philip de Reuver, Hari Nathan

PDF Pages: 3227-3239 Full Text (907) Reporting Checklist COI Form Open Access

A descriptive analysis of the characteristics, treatment response and prognosis of hepatic dominant solid tumors undergoing selective internal radiation therapy (SIRT)

Benedict Gosztonyi, Bernhard Pestalozzi, David Kenkel, Ivette Engel-Bicik, Philipp A. Kaufmann, Valerie Treyer, Alexander R. Siebenhüner

PDF Pages: 3240-3253 Full Text (1086) Reporting Checklist Data Sharing Statement COI Form Open Access

Curcumin inhibits pancreatic cancer cell proliferation by regulating Beclin1 expression and inhibiting the hypoxia-inducible factor-1α-mediated glycolytic pathway

Wencheng Guo, Yamei Ding, Chunmei Pu, Zhu Wang, Wei Deng, Xiaochao Jin

PDF Pages: 3254-3262 Full Text (2093) Reporting Checklist Data Sharing Statement COI Form Open Access

MicroRNA-543 controls pancreatic cancer development by LINC00847-microRNA-543-STK31 axis

Yan Liu, Jun Wei, Chao Wang, Zihui Meng, Duqiang Luo, Xiaoling Zhao, Ruizhi Hou

PDF Pages: 3263-3277 Full Text (1001) Reporting Checklist Data Sharing Statement COI Form Open Access

Downregulation of LINC01426 inhibits the proliferation and migration of human pancreatic cancer cells in vivo and in vitro

Zhixiang Ming, Ruoyi Zhang, Jianhua Xu, Wei Ding, Lei Qin

PDF Pages: 3278-3289 Full Text (769) Reporting Checklist Data Sharing Statement COI Form Open Access

Development and validation of an XGBoost model to predict 5-year survival in elderly patients with intrahepatic cholangiocarcinoma after surgery: a SEER-based study

Qiuping Xu, Xiaoling Lu

PDF Pages: 3290-3299 Full Text (1464) Reporting Checklist COI Form Open Access

Study Protocol

Low-dose apatinib combined with camrelizumab and the SOX regimen in the neoadjuvant treatment of locally advanced gastric/gastroesophageal junction adenocarcinoma (SPACE-neo): a protocol for an open-label, single-arm, clinical trial

Lanlan Pan, Yitong Tian, Kangxin Wang, Jie Tang, Jin Liu, Jiaguang Zhang, Min Wang, Jie Liu, Hao Xu, Xiaofeng Chen

PDF Pages: 3300-3313 Full Text (1299) COI Form Open Access

Case Report

Gemcitabine-induced thrombotic microangiopathy treated with eculizumab: a case report

Lisa Van den Eeckhaut, Heidi Hannon, Marie Schurgers, Els Monsaert, Kathleen Claes

PDF Pages: 3314-3320 Full Text (1294) Reporting Checklist COI Form Open Access

Congenital cardiac liver cirrhosis with combined hepatocellular-cholangiocarcinoma—a case report

Imane El Dika, Jinru Shia, Carol L. Chen, Viktoriya Paroder, Alan Carver, Ali Shamseddine, Deborah Mukherji, Bhawna Sirohi, Precious Takondwa Makondi, Clara Asseily, Charbel F. Matar, Rawad Elias, Emily Slater, Marlon Steven Rosenbaum, Rekha Paramesawaran, William Breitbart, Ghassan K. Abou-Alfa

PDF Pages: 3321-3328 Full Text (1722) Reporting Checklist COI Form Open Access